多基因风险评分（PRSs）在预测胰腺癌中的效用：对常见变异和混合评分的系统评价与荟萃分析，并对罕见变异分析有所洞察

Utility of Polygenic Risk Scores (PRSs) in Predicting Pancreatic Cancer: A Systematic Review and Meta-Analysis of Common-Variant and Mixed Scores with Insights into Rare Variant Analysis.

作者信息

Verras Georgios Ioannis, Hamady Zaed Z, Collins Andrew, Tapper William

机构信息

School of Human Development and Health, Faculty of Medicine, University of Southampton, Southampton SO16 6YD, UK.

Department of General Surgery, University Hospital Southampton, Southampton SO16 6YD, UK.

出版信息

Cancers (Basel). 2025 Jan 13;17(2):241. doi: 10.3390/cancers17020241.

DOI:10.3390/cancers17020241

PMID:39858023

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11764467/

Abstract

Pancreatic adenocarcinoma is the most common histological subtype of pancreatic cancer, representing approximately 85% of all cases [...].

摘要

胰腺腺癌是胰腺癌最常见的组织学亚型，约占所有病例的85%[...]。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e8f3/11764467/f084f24d9d63/cancers-17-00241-g001.jpg

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多基因风险评分（PRSs）在预测胰腺癌中的效用：对常见变异和混合评分的系统评价与荟萃分析，并对罕见变异分析有所洞察

Utility of Polygenic Risk Scores (PRSs) in Predicting Pancreatic Cancer: A Systematic Review and Meta-Analysis of Common-Variant and Mixed Scores with Insights into Rare Variant Analysis.

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多基因风险评分（PRSs）在预测胰腺癌中的效用：对常见变异和混合评分的系统评价与荟萃分析，并对罕见变异分析有所洞察

Utility of Polygenic Risk Scores (PRSs) in Predicting Pancreatic Cancer: A Systematic Review and Meta-Analysis of Common-Variant and Mixed Scores with Insights into Rare Variant Analysis.

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