Kovács Barbara Petra, Balog Júlia, Sebők Barbara, Keszthelyi Márton, Várbíró Szabolcs
Doctoral College, Semmelweis University, 1085 Budapest, Hungary.
Workgroup for Science Management, Semmelweis University Doctoral College, 1085 Budapest, Hungary.
Life (Basel). 2024 Dec 27;15(1):18. doi: 10.3390/life15010018.
According to World Health Organization (WHO) data, 16% of people are affected by infertility across the globe. One underlying factor is the age-related decline of ovarian reserve (DOR), which can lead to a higher chance of infertility and has no widely accepted treatment currently. Specific supplements and moderate exercise have been shown to improve fertility; however, there is no consensus to date on the type of exercise providing the best results. Our goal is to develop a novel exercise program combined with natural supplements for the improvement of fertility. We also propose a single-centered, randomized, open-label clinical trial using our newly developed exercise in the intervention group, compared to walking and no exercise in the other groups, to investigate the benefits of this exercise program in the future. In this study, we developed a structured, novel combination of exercises focusing on the pelvic and ovarian regions, core strengthening and improvement of blood circulation in this region. The 70 min full body "reproductive gymnastics", includes strengthening, stretching, and relaxation exercises combined with yoga-inspired moves and diaphragmatic breathing with meditation elements to activate the parasympathetic pathway and stress relief. We believe we can improve fertility through the combination of natural supplements and our targeted, moderate physiotherapy program in women with DOR.
根据世界卫生组织（WHO）的数据，全球16%的人受到不孕不育的影响。一个潜在因素是与年龄相关的卵巢储备功能下降（DOR），这可能导致更高的不孕几率，并且目前尚无被广泛接受的治疗方法。特定的补充剂和适度运动已被证明可以提高生育能力；然而，迄今为止，对于哪种运动能产生最佳效果尚无共识。我们的目标是开发一种结合天然补充剂的新型运动方案，以提高生育能力。我们还提议进行一项单中心、随机、开放标签的临床试验，在干预组中使用我们新开发的运动，与其他组的步行和不运动进行比较，以研究该运动方案未来的益处。在这项研究中，我们开发了一种结构化的、新颖的运动组合，重点关注盆腔和卵巢区域、核心力量训练以及该区域血液循环的改善。这套70分钟的全身“生殖体操”，包括强化、拉伸和放松练习，结合了受瑜伽启发的动作以及带有冥想元素的膈肌呼吸，以激活副交感神经通路并缓解压力。我们相信，通过将天然补充剂与针对卵巢储备功能下降女性的有针对性的适度物理治疗方案相结合，我们可以提高生育能力。
