Amodio Emanuele, Di Maria Gabriele, Lodico Manuela, Genovese Dario, Muggeo Vito M R, Maniscalco Laura, Conti Michela, Sergio Maria, Cascio Antonio, Tuttolomondo Antonino, Matranga Domenica, Vitale Francesco, Enea Marco
Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties, University of Palermo, 90127 Palermo, Italy.
Department of Economics, Business and Statistics, University of Palermo, 90128 Palermo, Italy.
J Clin Med. 2025 Jan 8;14(2):353. doi: 10.3390/jcm14020353.
: Stroke is a leading cause of mortality and disability worldwide, ranking as the second most common cause of death and the third in disability-adjusted life-years lost. Ischaemic stroke, which constitutes the majority of cases, poses significant public health and economic challenges. This study evaluates trends in ischaemic stroke hospitalisations in Italy from 2008 to 2022, focusing on differences before and after the COVID-19 pandemic. : We analysed ischaemic stroke hospitalisations among individuals admitted through emergency services using Italian hospital discharge records from 2008 to 2022. Poisson Inverse Gaussian regression was employed to assess hospitalisation trends, accounting for age, sex, and geographic variations. : Among 1,689,844 ischaemic stroke hospitalisations, there was a marked age-related increase, particularly among individuals aged 74 and older, with males consistently showing higher rates. Hospitalisation trends demonstrated a 20% reduction over 15 years, suggesting improvements in stroke prevention and treatment. However, there was a slight increase in rates during the COVID-19 period, despite the overall declining trend, highlighting the potential healthcare challenges experienced during the pandemic. Multivariable analysis confirmed age and male sex as significant risk factors. : This study underscores the age-related increase in stroke hospitalisation rates, emphasising the need for targeted prevention strategies for elderly populations. The overall reduction in stroke hospitalisation rates reflects advancements made in healthcare, although the impact of COVID-19 on access to stroke care is evident. Future policies must address the pandemic's effects on stroke care continuity and prioritise interventions tailored to age and sex.
中风是全球死亡和残疾的主要原因，在死亡原因中排名第二，在伤残调整生命年损失方面排名第三。缺血性中风占大多数病例，带来了重大的公共卫生和经济挑战。本研究评估了2008年至2022年意大利缺血性中风住院情况的趋势，重点关注新冠疫情前后的差异。我们使用2008年至2022年意大利医院出院记录，分析了通过急诊入院的个体中的缺血性中风住院情况。采用泊松逆高斯回归评估住院趋势，并考虑了年龄、性别和地理差异。在1689844例缺血性中风住院病例中，存在明显的与年龄相关的增加，特别是在74岁及以上的个体中，男性的发病率一直较高。住院趋势显示在15年中下降了20%，表明中风预防和治疗有所改善。然而，尽管总体呈下降趋势，但在新冠疫情期间发病率略有上升，突出了疫情期间面临的潜在医疗挑战。多变量分析证实年龄和男性性别是重要的风险因素。本研究强调了中风住院率与年龄相关的增加，强调需要针对老年人群制定有针对性的预防策略。中风住院率的总体下降反映了医疗保健方面取得的进展，尽管新冠疫情对中风护理可及性的影响显而易见。未来的政策必须应对疫情对中风护理连续性的影响，并优先考虑针对年龄和性别的干预措施。
