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牙髓病学病理学中的微生物动态——从细菌感染到治疗干预——一篇叙述性综述

Microbial Dynamics in Endodontic Pathology-From Bacterial Infection to Therapeutic Interventions-A Narrative Review.

作者信息

Wieczorkiewicz Klara, Jarząbek Anna, Bakinowska Estera, Kiełbowski Kajetan, Pawlik Andrzej

机构信息

Laboratory of Paediatric Dentistry, Pomeranian Medical University in Szczecin, Powstancow Wlkp 72, 70-111 Szczecin, Poland.

Department of Physiology, Pomeranian Medical University, 70-111 Szczecin, Poland.

出版信息

Pathogens. 2024 Dec 29;14(1):12. doi: 10.3390/pathogens14010012.

DOI:10.3390/pathogens14010012
PMID:39860973
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11768076/
Abstract

Endodontic infection is a penetration of microorganisms into the dental pulp. Bacteria are the most common entities that induce an infection. This state is associated with significant pain and discomfort. Therapeutic intervention involves removal of infected pulp from the tooth and roots, which eliminates viable tissue, thus creating a tooth less resistant to mechanical pressure. Studies suggest that there are several types of bacteria most commonly associated with endodontic infections. Furthermore, it is considered that different types of pathogens could play a major role in primary and secondary endodontic infections. The aim of this review is to summarize major bacteria involved in the process of endodontic infection. Furthermore, we discuss the bacterial properties that allow them to penetrate dental pulp and hypothesize about possible future treatment strategies.

摘要

牙髓感染是微生物侵入牙髓。细菌是引发感染最常见的病原体。这种状态会伴有严重的疼痛和不适。治疗干预包括从牙齿和牙根中去除感染的牙髓,这会清除有活力的组织,从而使牙齿对机械压力的抵抗力降低。研究表明,有几种细菌最常与牙髓感染相关。此外,人们认为不同类型的病原体可能在原发性和继发性牙髓感染中起主要作用。本综述的目的是总结牙髓感染过程中涉及的主要细菌。此外,我们还将讨论使它们能够侵入牙髓的细菌特性,并对未来可能的治疗策略进行推测。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c53/11768076/7930fbbebbbe/pathogens-14-00012-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c53/11768076/5ca6146c5c6c/pathogens-14-00012-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c53/11768076/dda8a9a4af5e/pathogens-14-00012-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c53/11768076/7930fbbebbbe/pathogens-14-00012-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c53/11768076/5ca6146c5c6c/pathogens-14-00012-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c53/11768076/dda8a9a4af5e/pathogens-14-00012-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9c53/11768076/7930fbbebbbe/pathogens-14-00012-g003.jpg

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Analysis of the microbial community diversity in various regions of the healthy oral cavity.分析健康口腔不同区域的微生物群落多样性。
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Clinical Investigation of Bacteriome in Primary Endodontic Infections With Apical Periodontitis Using High-Throughput Sequencing Analysis.
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Linking periodontal pathogens with endoperio lesions.将牙周病原体与牙髓牙周联合病变相联系。
Bioinformation. 2024 May 31;20(5):583-586. doi: 10.6026/973206300200583. eCollection 2024.
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