Yin Chunjie, Gan Qian, Xu Peipei, Yang Titi, Xu Juan, Cao Wei, Wang Hongliang, Pan Hui, Luo Ruihe, Xiao Hui, Wang Kai, Zhang Qian
School of Public Health, Xinjiang Medical University, Urumqi 830017, China.
Chinese Center for Disease Control and Prevention, National Institute for Nutrition and Health, Key Laboratory of Public Nutrition and Health, National Health Commission of the People's Republic of China, Beijing 100050, China.
Nutrients. 2025 Jan 12;17(2):260. doi: 10.3390/nu17020260.
BACKGROUND/OBJECTIVES: The prevalence of both myopia and obesity is increasing among children and adolescents around the world. We aimed to examine the association between weight status and myopia in Chinese children and adolescents.
The analysis included 35,108 participants aged 6-17 from a nationwide cross-sectional survey.
Our results indicated that girls with overweight and obesity had higher odds ratio (OR) of myopia and mild myopia: ages 6-8 (OR = 1.33, 95% CI: 1.01-1.76; OR = 1.71, 95% CI: 1.14-2.55) and 9-11 (OR = 1.22, 95% CI: 1.03-1.44; OR = 1.31, 95% CI: 1.06-1.62). Myopic boys had higher body fat percentages (BFP) at ages 6-8 (β = 1.18, 95% CI: 0.38-1.98), 9-11 (β = 0.58, 95% CI: 0.08-1.07), and 15-17 (β = 0.42, 95% CI: 0.03-0.80), and higher body mass index (BMI) at ages 9-11 (β = 0.30, 95% CI: 0.12-0.48) and 12-14 (β = 0.19, 95% CI: 0.02-0.38). Girls had higher BFP at ages 9-11 (β = 0.62, 95% CI: 0.19-1.05) and 12-14 (β =0.53, 95% CI: 0.19-0.88) and higher BMI at 9-11 (β = 0.53, 95% CI: 0.34-0.73). Furthermore, the dose-response curves revealed a significant gender- and age-specific association between BMI, BFP, and myopia odds ratio.
the study found an association between overweight or obesity and myopia in girls aged 6-11, and indicated that high BFP and BMI are associated with myopia, varying by sex and age.
背景/目的：全球儿童和青少年中近视和肥胖的患病率均在上升。我们旨在研究中国儿童和青少年体重状况与近视之间的关联。
该分析纳入了一项全国性横断面调查中的35108名6至17岁的参与者。
我们的结果表明，超重和肥胖女孩患近视和轻度近视的比值比（OR）更高：6至8岁（OR = 1.33，95%置信区间：1.01 - 1.76；OR = 1.71，95%置信区间：1.14 - 2.55）和9至11岁（OR = 1.22，95%置信区间：1.03 - 1.44；OR = 1.31，95%置信区间：1.06 - 1.62）。近视男孩在6至8岁（β = 1.18，95%置信区间：0.38 - 1.98）、9至11岁（β = 0.58，95%置信区间：0.08 - 1.07）和15至17岁（β = 0.42，95%置信区间：0.03 - 0.80）时体脂百分比（BFP）较高，在9至11岁（β = 0.30，95%置信区间：0.12 - 0.48）和12至14岁（β = 0.19，95%置信区间：0.02 - 0.38）时体重指数（BMI）较高。女孩在9至11岁（β = 0.62，95%置信区间：0.19 - 1.05）和12至14岁（β = 0.53，95%置信区间：0.19 - 0.88）时BFP较高，在9至11岁（β = 0.53，95%置信区间：0.34 - 0.73）时BMI较高。此外，剂量反应曲线显示BMI、BFP与近视比值比之间存在显著的性别和年龄特异性关联。
该研究发现6至11岁女孩超重或肥胖与近视之间存在关联，并表明高BFP和BMI与近视相关，且因性别和年龄而异。
