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胆固醇酯增加红细胞膜的通透性。

[Cholesterol ester increases the permeability of erythrocyte membrane].

作者信息

Ivanov A S, Karvat R G, Mol'nar A A, Khalilov E M

出版信息

Biofizika. 1985 Mar-Apr;30(2):269-72.

PMID:3986226
Abstract

The effect of cholesteryl palmitate on erythrocyte membrane permeability for K+ and hemoglobin was studied. Cholesterol ether was incorporated into the erythrocyte membrane by liposomes containing cholesteryl palmitate and lecithin or by dispersion of cholesteryl palmitate. It was shown that cholesteryl palmitate considerably increases permeability of the erythrocyte membrane for K+ and hemoglobin. The leakage of K+ and hemoglobin from red blood cells is not accompanied by cell destruction.

摘要

研究了棕榈酰胆固醇对红细胞膜对钾离子和血红蛋白的通透性的影响。通过含有棕榈酰胆固醇和卵磷脂的脂质体或将棕榈酰胆固醇分散,将胆固醇醚掺入红细胞膜中。结果表明,棕榈酰胆固醇显著增加了红细胞膜对钾离子和血红蛋白的通透性。红细胞中钾离子和血红蛋白的泄漏并不伴随着细胞破坏。

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