Dablan Ali, Bayrak Osman Nuri, Mutlu İlhan Nahit, Barut Hamit Yücel, Akgün Elife, Bağbudar Sidar, Kılıçkesmez Özgür
Basaksehir Cam and Sakura City Hospital, İstanbul, Turkey.
Abdom Radiol (NY). 2025 Jan 25. doi: 10.1007/s00261-025-04797-z.
To evaluate the safety, diagnostic accuracy, and factors influencing the diagnostic yield of ultrasound (US)-guided omental biopsies.
This retrospective study included 109 patients who underwent US-guided omental biopsies between June 2020 and June 2024. Pre-biopsy diagnostic images (CT, MRI, or [18 F]FDG PET/CT) were reviewed. Diagnostic accuracy, sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and adverse events were evaluated. Surgical or clinical diagnoses with follow-up served as the diagnostic reference standard. Associations between diagnostic yield and findings on pre-biopsy imaging and biopsy US were explored.
The study achieved a technical success rate of 100%. Initial biopsy results showed a sensitivity of 82.6%, specificity of 100%, PPV of 100%, NPV of 60.5%, and diagnostic accuracy of 86.2%. The pre-biopsy imaging modality was not related to diagnostic accuracy. Ascites interposition on the puncture route was significantly higher in patients without diagnostic accuracy (73.3% vs. 30.9%, p = 0.002). Deeper lesions exhibited lower diagnostic accuracy (p = 0.003). No major or minor complications were associated with the biopsies.
Percutaneous omental biopsy is an effective and safe method for evaluating omental abnormalities. Depth from the needle entry site and the presence of ascites along the puncture route were identified as factors affecting diagnostic accuracy. The choice of imaging modality did not impact diagnostic outcomes, highlighting the importance of lesion-specific factors in the planning of biopsies.
评估超声（US）引导下网膜活检的安全性、诊断准确性以及影响诊断率的因素。
这项回顾性研究纳入了2020年6月至2024年6月期间接受US引导下网膜活检的109例患者。回顾活检前的诊断图像（CT、MRI或[18F]FDG PET/CT）。评估诊断准确性、敏感性、特异性、阳性预测值（PPV）、阴性预测值（NPV）和不良事件。以手术或临床诊断及随访结果作为诊断参考标准。探讨活检前影像学检查结果与活检超声检查结果之间与诊断率的关联。
该研究的技术成功率为100%。初次活检结果显示敏感性为82.6%，特异性为100%，PPV为100%，NPV为60.5%，诊断准确性为86.2%。活检前的影像学检查方式与诊断准确性无关。穿刺路径上有腹水阻隔的患者中诊断不准确的比例显著更高（73.3%对30.9%，p = 0.002）。病变位置较深的患者诊断准确性较低（p = 0.003）。活检未出现严重或轻微并发症。
经皮网膜活检是评估网膜异常的一种有效且安全的方法。穿刺点至病变的深度以及穿刺路径上腹水的存在被确定为影响诊断准确性的因素。影像学检查方式的选择不影响诊断结果，突出了病变特异性因素在活检规划中的重要性。
