Mori M, Sugimachi K, Ohiwa T, Okamura T, Tamura S, Inokuchi K
Br J Surg. 1985 Apr;72(4):289-91. doi: 10.1002/bjs.1800720415.
The clinicopathological characteristics of early gastric carcinoma (EGC) in 23 Japanese under 30 years of age were reviewed and the findings compared with data on 53 patients over age 70. In the young patients, there was a female preponderance, a macroscopic solitary lesion and the cancer was of the poorly differentiated type without intestinal metaplasia in the surrounding mucosa. In the old patients, there was a male preponderance; about half the number of patients had macroscopically elevated lesions and 10 of the 53 had a multifocal gastric carcinoma. Here, most lesions were well to moderately differentiated types with intestinal metaplasia in the surrounding area. Growth patterns of EGC in the young patients were analysed. Curative operations with dissection of regional lymph nodes were done in all the young patients. Metastases to the regional lymph nodes were present in only 2 of 23. Twenty of twenty-three followed for 5 years or longer are well.
回顾了23例30岁以下日本早期胃癌（EGC）患者的临床病理特征，并将结果与53例70岁以上患者的数据进行比较。年轻患者中女性居多，肉眼可见为孤立性病变，癌症为低分化型，周围黏膜无肠化生。老年患者中男性居多；约半数患者肉眼可见隆起性病变，53例中有10例为多灶性胃癌。此处，大多数病变为高分化至中分化型，周围区域有肠化生。分析了年轻患者EGC的生长模式。所有年轻患者均进行了区域淋巴结清扫的根治性手术。23例中仅2例出现区域淋巴结转移。23例中有20例随访5年或更长时间，情况良好。
