Colgan M P, Kingston W, Shanik D G
Br J Surg. 1985 Apr;72(4):313-4. doi: 10.1002/bjs.1800720424.
Carotid endarterectomy is well established in the treatment of selected cases of atherosclerosis of the carotid bifurcation; however, its role in the management of asymptomatic stenosis of the internal carotid artery remains controversial. Over a 4 year period 190 patients with 209 asymptomatic stenoses of the internal carotid artery were prospectively studied by means of Doppler ultrasound in combination with real time spectral analysis to determine the natural history of asymptomatic carotid stenosis. We report a cumulative stroke-free survival of 97 per cent at 3 years and we therefore question the merit of prophylactic endarterectomy in the management of asymptomatic carotid disease.
颈动脉内膜切除术在治疗特定的颈动脉分叉处动脉粥样硬化病例方面已得到充分确立;然而,其在无症状性颈内动脉狭窄管理中的作用仍存在争议。在4年期间,对190例患有209处无症状性颈内动脉狭窄的患者进行了前瞻性研究,采用多普勒超声结合实时频谱分析来确定无症状性颈动脉狭窄的自然病程。我们报告3年时无卒中累积生存率为97%,因此我们质疑预防性内膜切除术在无症状性颈动脉疾病管理中的价值。