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无症状性颈动脉狭窄:预防性动脉内膜切除术是否合理?

Asymptomatic carotid stenosis: is prophylactic endarterectomy justifiable?

作者信息

Colgan M P, Kingston W, Shanik D G

出版信息

Br J Surg. 1985 Apr;72(4):313-4. doi: 10.1002/bjs.1800720424.

DOI:10.1002/bjs.1800720424
PMID:3986487
Abstract

Carotid endarterectomy is well established in the treatment of selected cases of atherosclerosis of the carotid bifurcation; however, its role in the management of asymptomatic stenosis of the internal carotid artery remains controversial. Over a 4 year period 190 patients with 209 asymptomatic stenoses of the internal carotid artery were prospectively studied by means of Doppler ultrasound in combination with real time spectral analysis to determine the natural history of asymptomatic carotid stenosis. We report a cumulative stroke-free survival of 97 per cent at 3 years and we therefore question the merit of prophylactic endarterectomy in the management of asymptomatic carotid disease.

摘要

颈动脉内膜切除术在治疗特定的颈动脉分叉处动脉粥样硬化病例方面已得到充分确立;然而,其在无症状性颈内动脉狭窄管理中的作用仍存在争议。在4年期间,对190例患有209处无症状性颈内动脉狭窄的患者进行了前瞻性研究,采用多普勒超声结合实时频谱分析来确定无症状性颈动脉狭窄的自然病程。我们报告3年时无卒中累积生存率为97%,因此我们质疑预防性内膜切除术在无症状性颈动脉疾病管理中的价值。

相似文献

1
Asymptomatic carotid stenosis: is prophylactic endarterectomy justifiable?无症状性颈动脉狭窄:预防性动脉内膜切除术是否合理?
Br J Surg. 1985 Apr;72(4):313-4. doi: 10.1002/bjs.1800720424.
2
Stenosis following carotid endarterectomy. Its implication in management of asymptomatic carotid stenosis.颈动脉内膜切除术后的狭窄。其在无症状性颈动脉狭窄管理中的意义。
Arch Surg. 1984 Sep;119(9):1033-5. doi: 10.1001/archsurg.1984.01390210037009.
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Stenosis following carotid endarterectomy.
J Cardiovasc Surg (Torino). 1985 May-Jun;26(3):300-2.
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Role of carotid endarterectomy in asymptomatic carotid stenosis. A Veterans Administration Cooperative Study.颈动脉内膜切除术在无症状性颈动脉狭窄中的作用。一项退伍军人管理局合作研究。
Stroke. 1986 May-Jun;17(3):534-9. doi: 10.1161/01.str.17.3.534.
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Carotid artery stenosis - hemodynamic significance and clinical course.颈动脉狭窄——血流动力学意义及临床病程
JAMA. 1981 Apr 10;245(14):1438-41. doi: 10.1001/jama.245.14.1438.
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Long-term results after carotid endarterectomy for carotid artery stenosis with contralateral occlusion.
Ann Vasc Surg. 1990 Jul;4(4):323-7. doi: 10.1007/BF02000493.
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[Therapy of carotid stenosis in contralateral occlusion of the internal carotid artery].
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Carotid endarterectomy to correct asymptomatic carotid stenosis: ten years later.
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Symptomatic carotid ischaemic events: safest and most cost effective way of selecting patients for angiography, before carotid endarterectomy.有症状的颈动脉缺血事件:在颈动脉内膜切除术之前,选择患者进行血管造影的最安全且最具成本效益的方法。
BMJ. 1990 Jun 9;300(6738):1485-91. doi: 10.1136/bmj.300.6738.1485.
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Monitoring cerebral perfusion during carotid endarterectomy.颈动脉内膜切除术期间的脑灌注监测。
J Cardiovasc Surg (Torino). 1990 Jan-Feb;31(1):112-4.

引用本文的文献

1
Noninvasive assessment of stroke risk in asymptomatic and nonhemispheric patients with suspected carotid disease. Five-year follow-up of 294 unoperated and 81 operated patients.对疑似颈动脉疾病的无症状和非半球性患者进行中风风险的无创评估。对294例未接受手术的患者和81例接受手术的患者进行了五年随访。
Ann Surg. 1985 Oct;202(4):491-504. doi: 10.1097/00000658-198510000-00009.