Busuttil R W, Baker J D, Davidson R K, Machleder H I
JAMA. 1981 Apr 10;245(14):1438-41. doi: 10.1001/jama.245.14.1438.
Two hundred fifteen patients with a history of either stroke, transient ischemic attack (TIA), or asymptomatic carotid bruit underwent noninvasive carotid artery testing using oculopneumoplethysmography. Of patients with hemodynamically significant stenosis, 51 (40.8%) underwent endarterectomy, and 74 (59.2%) were treated nonoperatively. The incidence of stroke in the nonoperated group was 12/74 (16.2%) compared with only 1/51 (1.9%) in the operated group. Similarly, recurrent TIA occurred in 29/74 (39.2%) of the nonoperated group vs 9/51 (17.6%) of the operated. In nonhemodynamically significant carotid stenosis, the risk of cerebrovascular death and stroke was exceedingly low: 2/90 (2.2%). Patients with hemodynamically significant stenosis treated nonoperatively have a greater risk of cerebrovascular death, stroke, and TIA than patients treated with carotid endarterectomy.
215例有中风、短暂性脑缺血发作（TIA）或无症状颈动脉杂音病史的患者接受了眼体积描记法的无创颈动脉检测。在血流动力学显著狭窄的患者中，51例（40.8%）接受了内膜切除术，74例（59.2%）接受了非手术治疗。非手术组的中风发生率为12/74（16.2%），而手术组仅为1/51（1.9%）。同样，非手术组29/74（39.2%）发生复发性TIA，而手术组为9/51（17.6%）。在血流动力学不显著的颈动脉狭窄中，脑血管死亡和中风的风险极低：2/90（2.2%）。与接受颈动脉内膜切除术的患者相比，非手术治疗的血流动力学显著狭窄患者发生脑血管死亡、中风和TIA的风险更高。
