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对于65岁以下Kellgren-Lawrence 3-4级内侧单髁膝关节骨关节炎患者,间隔型胫骨截骨术与开放性楔形高位胫骨截骨术及单髁膝关节置换术的比较

Spacer-type tibial osteotomy versus open wedge high tibial osteotomy and unicompartmental knee arthroplasty for Kellgren-Lawrence grade 3-4 medial unicompartmental knee osteoarthritis in patients younger than 65 years.

作者信息

Zhang Yi, Yin Xiangzhi, Chen Jinli, Zhang Yingze, Yu Tengbo

机构信息

Department of Sports Medicine, Affiliated Hospital of Qingdao University, 59 Haier Road, Laoshan District, Qingdao, Shandong Province, 266075, China.

Traumatic Orthopedics Institute of Shandong, Affiliated Hospital of Qingdao University, 16 Jiangsu Road, Shinan District, Qingdao, Shandong Province, 266001, China.

出版信息

J Orthop Surg Res. 2025 Jan 27;20(1):99. doi: 10.1186/s13018-025-05533-5.

Abstract

BACKGROUND

Spacer-type tibial osteotomy have been proven a novel and effective osteotomy to treat osteoarthritis, while lack of comparison with other surgical methods in younger patients. This study aims to evaluate the short-term clinical outcomes of spacer-type tibial osteotomy versus open wedge high tibial osteotomy (OWHTO) and unicompartmental knee arthroplasty (UKA) for Kellgren-Lawrence (K-L) grade 3-4 osteoarthritis (OA) in patients younger than 65 years.

METHODS

This retrospective study analyzed a total of 224 patients with K-L grade 3-4 knee OA treated from March 2018 to November 2020. Three groups were created according to the operation type. The clinical outcomes recorded preoperatively and at 6, 12 and 24 months postoperatively were the range of motion (ROM), visual analogue scale (VAS), American Knee Society Score (KSS), Western Ontario and McMaster Universities Global (WOMAC) score, operation time, length of incision, relevant complications and failures. Radiographic parameters were measured to evaluate the correction of varus deformity.

RESULTS

The cohort comprised 224 patients; 70 underwent spacer-type tibial osteotomy, 73 underwent OWHTO, and 81 underwent UKA. The spacer group had the shortest incision (P = 0.000), least amount of bleeding (P = 0.000), and shortest operation time (P = 0.000). UKA achieved the most significant pain relief based on VAS (P = 0.014), KSS pain score (0.030), and WOMAC score (P = 0.000) at 6 months postoperatively, but there were no differences between three groups at 12 and 24 months postoperatively. The spacer and OWHTO groups achieved significantly greater ROM changes compared with the UKA group (all P = 0.000). The complication rate did not significantly differ between the three groups. No surgical failures were identified in HTO but two spacer dislocations in spacer group and three polyethylene dislocations in UKA.

CONCLUSION

For younger patients with K-L grade 3-4 OA, OWHTO seems to be the most appropriate method through clinical comparisons. Although spacer-type tibial osteotomy offers shorter operation time and comparable clinical outcomes, it also has extended recovery phase, additional fibular incision and the risk of spacer dislocation, which did not appear to be superior to OWHTO and UKA under the indications outlined in this study.

TRIAL REGISTRATION

Retrospectively registered, QYFY WZLL 27,021.

摘要

背景

间隔型胫骨截骨术已被证明是一种治疗骨关节炎的新型有效截骨术,但在年轻患者中缺乏与其他手术方法的比较。本研究旨在评估间隔型胫骨截骨术与开放性楔形高位胫骨截骨术(OWHTO)和单髁膝关节置换术(UKA)治疗65岁以下Kellgren-Lawrence(K-L)3-4级骨关节炎(OA)的短期临床疗效。

方法

这项回顾性研究分析了2018年3月至2020年11月期间治疗的224例K-L 3-4级膝骨关节炎患者。根据手术类型分为三组。术前以及术后6、12和24个月记录的临床疗效包括活动范围(ROM)、视觉模拟评分(VAS)、美国膝关节协会评分(KSS)、西安大略和麦克马斯特大学骨关节炎指数(WOMAC)评分、手术时间、切口长度、相关并发症和失败情况。测量影像学参数以评估内翻畸形的矫正情况。

结果

该队列包括224例患者;70例行间隔型胫骨截骨术,73例行OWHTO,81例行UKA。间隔型胫骨截骨术组切口最短(P = 0.000),出血量最少(P = 0.000),手术时间最短(P = 0.000)。UKA在术后6个月时基于VAS(P = 0.014)、KSS疼痛评分(0.030)和WOMAC评分(P = 0.000)实现了最显著的疼痛缓解,但术后12个月和24个月时三组之间无差异。与UKA组相比,间隔型胫骨截骨术组和OWHTO组的ROM变化明显更大(所有P = 0.000)。三组之间的并发症发生率无显著差异。HTO组未发现手术失败,但间隔型胫骨截骨术组有2例间隔器脱位,UKA组有3例聚乙烯脱位。

结论

对于K-L 3-4级OA的年轻患者,通过临床比较,OWHTO似乎是最合适的方法。尽管间隔型胫骨截骨术手术时间较短且临床疗效相当,但它也有恢复阶段延长、额外的腓骨切口以及间隔器脱位的风险,在本研究所述的适应症下,它似乎并不优于OWHTO和UKA。

试验注册

回顾性注册,QYFY WZLL 27,021。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/367f/11771026/bb1a472e25a8/13018_2025_5533_Fig1_HTML.jpg

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