Taurine and hypotaurine inhibit light-induced lipid peroxidation and protect rod outer segment structure.
作者信息
Pasantes-Morales H, Cruz C
出版信息
Brain Res. 1985 Mar 18;330(1):154-7. doi: 10.1016/0006-8993(85)90018-6.
PMID:3986537
Abstract
Exposure of isolated frog rod outer segments to light (5000 lux) induces membrane disorganization and swelling. An increase of about 50% on lipid peroxidation, measured by the extent of malonaldehyde formation, accompanied the light-induced damage. Taurine and hypotaurine (25 mM) prevented the increase in lipid peroxidation, and provided an entire protection of rod outer segment structure.
摘要
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