Chen Matthew, Nguyen William, Haq Zaim, Guo William, Briley James
Department of Dermatology, Stony Brook University Medical Center, Stony Brook, New York, USA.
New York University Long Island School of Medicine, Mineola, New York, USA.
J Dtsch Dermatol Ges. 2025 Mar;23(3):330-338. doi: 10.1111/ddg.15630. Epub 2025 Jan 26.
Current research on hirsutism reveals disparities and knowledge deficiencies, particularly in underrepresented cohorts. Our objective is to scrutinize demographic variances in hirsutism rates.
Using the All of Us database, we conducted a cross-sectional analysis encompassing 172,401 women. We calculated prevalence rates and odds ratios for hirsutism among all women and those diagnosed with polycystic ovary syndrome (PCOS), examining various epidemiological factors.
Among the sampled women, hirsutism prevalence was 1.37%; in PCOS-afflicted females, it was 19.12%. Asian and Hispanic women exhibited diminished hirsutism likelihoods, whereas African-American counterparts showed elevated likelihood. Additionally, females aged 60-74 and 75+ demonstrated reduced hirsutism risks. Higher education and income above $ 50,000 correlated with heightened hirsutism likelihoods. PCOS females had substantially elevated hirsutism probabilities compared to the general female cohort. Within PCOS cohorts, African-American females had heightened hirsutism rates, while Hispanic females showed lower rates.
In conclusion, hirsutism prevalence is generally low among United States females but markedly higher in PCOS cases. Notably, certain racial, ethnic, and socioeconomic groups, both in the general populace and among PCOS patients, exhibit significantly disparate hirsutism rates.
目前关于多毛症的研究存在差异和知识不足,尤其是在代表性不足的人群中。我们的目标是仔细研究多毛症发病率的人口统计学差异。
我们使用“我们所有人”数据库,对172,401名女性进行了横断面分析。我们计算了所有女性以及被诊断为多囊卵巢综合征(PCOS)的女性中多毛症的患病率和比值比,研究了各种流行病学因素。
在抽样女性中,多毛症患病率为1.37%;在患有PCOS的女性中,患病率为19.12%。亚洲和西班牙裔女性患多毛症的可能性较低,而非洲裔美国女性的可能性较高。此外,60 - 74岁和75岁以上的女性患多毛症的风险较低。高等教育和收入超过5万美元与患多毛症的可能性增加相关。与普通女性队列相比,PCOS女性患多毛症的概率大幅升高。在PCOS队列中,非洲裔美国女性的多毛症发病率较高,而西班牙裔女性的发病率较低。
总之,美国女性中多毛症的患病率总体较低,但在PCOS病例中明显较高。值得注意的是,在普通人群和PCOS患者中,某些种族、民族和社会经济群体的多毛症发病率存在显著差异。