Li Feng
School of Physics, Australian Centre for Microscopy and Microanalysis, Sydney Nano Institute, The University of Sydney, Sydney, NSW 2006, Australia.
Biophys Rev (Melville). 2025 Jan 22;6(1):011302. doi: 10.1063/5.0217068. eCollection 2025 Mar.
The accurate detection of x-rays enables broad applications in various fields, including medical radiography, safety and security screening, and nondestructive inspection. Medical imaging procedures require the x-ray detection devices operating with low doses and high efficiency to reduce radiation health risks, as well as expect the flexible or wearable ones that offer more comfortable and accurate diagnosis experiences. Recently, halide perovskites have shown promising potential in high-performance, cost-effective x-ray detection owing to their attractive features, such as strong x-ray absorption, high-mobility-lifetime product, tunable bandgap, fast response, as well as low-cost raw materials, facile processing, and excellent flexibility. In this review, we comprehensively summarize the recent advances in halide perovskite x-ray detectors and imaging, focusing on their application potential in medical imaging technology. We highlight the recent demonstrations and optimizations of halide perovskite x-ray detectors and imaging and their application in medical radiography. Finally, we conclude by pointing out the challenges of perovskite x-ray detection devices for the clinical practical applications and by sharing our perspectives on the potential solutions for driving the field forward.
X射线的精确检测使其在包括医学放射成像、安全与安保筛查以及无损检测在内的各个领域都有广泛应用。医学成像程序要求X射线检测设备在低剂量和高效率下运行，以降低辐射健康风险，同时也期望有灵活或可穿戴的设备，能提供更舒适且准确的诊断体验。近年来，卤化物钙钛矿因其具有诸如强X射线吸收、高迁移率-寿命乘积、可调节带隙、快速响应以及低成本原材料、易于加工和出色柔韧性等吸引人的特性，在高性能、经济高效的X射线检测方面展现出了有前景的潜力。在本综述中，我们全面总结了卤化物钙钛矿X射线探测器及成像的最新进展，重点关注其在医学成像技术中的应用潜力。我们突出了卤化物钙钛矿X射线探测器及成像的近期示范和优化以及它们在医学放射成像中的应用。最后，我们指出钙钛矿X射线检测设备在临床实际应用中面临的挑战，并分享我们对推动该领域发展的潜在解决方案的看法。
