Abdel-Megeed Rehab M
Therapeutic Chemistry Department, National Research Center, El Buhouth St., Dokki, Cairo 12622, Egypt.
Toxicol Rep. 2024 Dec 31;14:101887. doi: 10.1016/j.toxrep.2024.101887. eCollection 2025 Jun.
Nanotechnology has significantly influenced the worldwide medical services sector during the past few decades. Biological collection approaches for nanoparticles are economical, non-toxic, and ecologically benign. This review provides up-to-date information on nanoparticle production processes and biological sources, including algae, plants, bacteria, fungus, actinomycetes, and yeast. The biological technique of generating nanoparticles has advantages over chemical, physical, and biological methods, including low-toxicity and friendly to the environment, thereby providing a viable option for therapeutic applications as s promising drug delivery system. In addition to aiding researchers, the bio-mediated, obtained nanoparticles also modify particles to promote both health and safety. We also looked at the important medicinal uses of nanoparticles, including their antifungal, antimicrobial, antiviral, antidiabetic, anti-inflammatory, and antioxidant properties. The current study highlights the findings of recent research in this field and discusses various methods proposed to describe the bio-mediated acquisition of novel nanoparticles.. The production of nanoparticles via biogenic sources possess various benefits, such as low cost, bioavailability, and environmental friendliness. In addition to the determination of the bioactive chemicals mediated by nanoparticle as well as the examination of the biochemical pathways and enzyme reactions. The major focus of this review is highlighting on the essential role of biogenic nanoparticles as promising drug delivery system.
在过去几十年中，纳米技术对全球医疗服务行业产生了重大影响。纳米颗粒的生物收集方法经济、无毒且生态友好。本综述提供了有关纳米颗粒生产工艺和生物来源的最新信息，包括藻类、植物、细菌、真菌、放线菌和酵母。与化学、物理和生物技术方法相比，生物法制备纳米颗粒具有低毒性和环境友好等优势，为作为一种有前景的药物递送系统的治疗应用提供了可行选择。除了帮助研究人员外，生物介导获得的纳米颗粒还对颗粒进行改性以促进健康和安全。我们还研究了纳米颗粒的重要药用用途，包括其抗真菌、抗菌、抗病毒、抗糖尿病、抗炎和抗氧化特性。当前的研究突出了该领域近期研究的结果，并讨论了为描述新型纳米颗粒的生物介导获取而提出的各种方法。通过生物源生产纳米颗粒具有多种益处，例如低成本、生物利用度高和环境友好。除了确定纳米颗粒介导的生物活性化学物质以及检查生化途径和酶反应外。本综述的主要重点是强调生物源纳米颗粒作为有前景的药物递送系统的重要作用。
