Zhang Xueqi, Song Kai, Miao Jiajun, Sun Shiang, Xiong Yongjie, He Shaojun
College of Animal Sciences, Anhui Science and Technology University, Fengyang, 233100, China.
Anhui Province Key Laboratory of Animal Nutrition Regulation and Health, Fengyang, 233100, China.
Trop Anim Health Prod. 2025 Jan 27;57(2):35. doi: 10.1007/s11250-025-04280-3.
This study was aim to investigate the effects of lipoic acid (ALA) on performance, meat quality, serum biochemistry and antioxidant function of broilers under heat stress (HS). Two hundred1-day-old Cobb broilers were randomly divided into four treatment groups and each treatment consisted of 4 replicates of 10 broilers each. The treatment group adopts a 2 × 2 two-factor setting, which is divided into two diets (basic diet or 250 mg/kg ALA diet) and two temperatures (24 ± 1℃ or 33 ± 1℃). Starting from the 28th day of age, broilers are kept at room temperature (24 ± 1℃) or exposed to cyclic HS (33 ± 1℃ from 8:00 am to 18:00, 24 ± 1℃ from 18:00 to 8:00 am). HS significantly decreased serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), direct bilirubin (D-BIL), total antioxidant capacity (T-AOC) and total superoxide dismutase (T-SOD). However, HS increased breast meat pH, serum uric acid (UA), total cholesterol (TC) and malondialdehyde (MDA). Dietary ALA significantly decreased leg meat shear force and water loss rate, serum total bilirubin(T-BIL), UA, triglyceride (TG) and MDA of broilers. However, it increased daily gain (ADG), serum D-BIL and T-SOD. There is a significant interaction between temperature and additives. HS can destroy the balance of the oxidation-antioxidant system, and lead to damage to liver and kidney function and confusion energy metabolism. Dietary ALA improves the antioxidant capacity of broilers, reduces the level of blood lipids and liver and kidney metabolism, and increases the daily gain of heat-stressed broilers.
本研究旨在探讨硫辛酸（ALA）对热应激（HS）条件下肉鸡生产性能、肉品质、血清生化指标及抗氧化功能的影响。200只1日龄科宝肉鸡随机分为4个处理组，每个处理组有4个重复，每个重复10只肉鸡。处理组采用2×2双因素设置，分为两种日粮（基础日粮或250mg/kg ALA日粮）和两种温度（24±1℃或33±1℃）。从28日龄开始，肉鸡分别饲养在室温（24±1℃）或暴露于周期性热应激环境（上午8:00至18:00为33±1℃，18:00至次日上午8:00为24±1℃）。热应激显著降低了血清谷丙转氨酶（ALT）、谷草转氨酶（AST）、直接胆红素（D-BIL）、总抗氧化能力（T-AOC）和总超氧化物歧化酶（T-SOD）。然而，热应激提高了胸肉pH值、血清尿酸（UA）、总胆固醇（TC）和丙二醛（MDA）。日粮添加ALA显著降低了肉鸡腿肉剪切力和失水率、血清总胆红素（T-BIL）、UA、甘油三酯（TG）和MDA。然而，它提高了日增重（ADG）、血清D-BIL和T-SOD。温度和添加剂之间存在显著交互作用。热应激会破坏氧化-抗氧化系统平衡，导致肝肾功能损伤和能量代谢紊乱。日粮添加ALA提高了肉鸡的抗氧化能力，降低了血脂水平以及肝脏和肾脏代谢负担，并增加了热应激肉鸡的日增重。
