Mueller-Leisse Johanna, Syrbius Giulia, Hillmann Henrike Aenne Katrin, Eiringhaus Joerg, Hohmann Stephan, Zormpas Christos, Karfoul Nizar, Duncker David, Veltmann Christian
Hannover Heart Rhythm Center, Department of Cardiology & Angiology, Hannover Medical School, Carl-Neuberg Str. 1, 30625, Hannover, Germany.
Heart Center Bremen, Electrophysiology Bremen, Bremen, Germany.
Herzschrittmacherther Elektrophysiol. 2025 Mar;36(1):70-74. doi: 10.1007/s00399-025-01065-x. Epub 2025 Jan 27.
The QRS axis of the electrocardiogram (ECG) is often considered in clinical practice, but its determination is frequently limited to a rough estimation, such as "normal", with left or right deviation, and superior or inferior in the case of premature ventricular complexes (PVCs). However, a more exact determination of the QRS axis may be warranted in certain scenarios, such as to determine the origin of PVCs more precisely, and is attainable by visual estimation using the hexaxial reference system.
The aim of this study was to determine how well such an estimation of the QRS axis would correlate with the axis calculated by formulas.
A PVC database from 2012-2020 was used to extract 12-lead ECGs of patients with outflow tract PVCs and analyze the QRS axes of regularly conducted beats as well as PVCs. QRS axes were determined visually by two physicians with the help of the hexaxial reference system to an accuracy of 10° on the one hand, and were calculated using three previously described formulas based on QRS voltages on the other.
A total of 216 QRS complexes from 108 patients were analyzed (108 regularly conducted beats and 108 PVCs). Estimated QRS axes of regularly conducted beats and PVCs were 39 ± 40° and 88 ± 15°, respectively. Calculated QRS axes of regularly conducted beats according to the three formulas were 37 ± 40°, 36 ± 40° and 35 ± 38°, respectively. Calculated QRS axes of PVCs according to the three formulas were 87 ± 15°, 87 ± 14° and 86 ± 16°, respectively. Correlation coefficients showed strong correlations between the estimated and the three calculated values for regularly conducted beats (0.98, 0.97 and 0.98) and PVCs (0.94, 0.94 and 0.94).
A sophisticated visual estimation of the QRS axis correlates well with voltage-based calculations and can therefore be considered sufficient for most purposes.
心电图(ECG)的QRS轴在临床实践中经常被考虑,但对其测定往往仅限于粗略估计,如“正常”,伴有左或右偏,对于室性早搏(PVC)则有上或下偏。然而,在某些情况下,可能需要更精确地测定QRS轴,例如更精确地确定PVC的起源,并且可以通过使用六轴参考系统进行视觉估计来实现。
本研究的目的是确定这种QRS轴估计与通过公式计算得出的轴的相关性如何。
使用2012年至2020年的PVC数据库,提取流出道PVC患者的12导联心电图,并分析正常传导搏动以及PVC的QRS轴。一方面,由两名医生借助六轴参考系统以10°的精度目视确定QRS轴,另一方面,使用基于QRS电压的三个先前描述的公式进行计算。
共分析了108例患者的216个QRS波群(108个正常传导搏动和108个PVC)。正常传导搏动和PVC的估计QRS轴分别为39±40°和88±15°。根据三个公式计算的正常传导搏动的QRS轴分别为37±40°、36±40°和35±38°。根据三个公式计算的PVC的QRS轴分别为87±15°、87±14°和86±16°。相关系数显示,正常传导搏动(0.98、0.97和0.98)和PVC(0.94、0.94和0.94)的估计值与三个计算值之间存在强相关性。
对QRS轴进行精细的视觉估计与基于电压的计算具有良好的相关性,因此在大多数情况下可认为是足够的。