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结痂性疥疮的初期阶段及可能的诊断特征:病例系列

Initial stage of crusted scabies and possible diagnostic characteristics: A case series.

作者信息

Li Wanchen, Song Lin, Guo Tao, Wu Yaliu, Li Xiaoli, Li Hongfeng, Li Jianjun, Li Simiao

机构信息

Department of Clinical Laboratory, The Second Hospital of Tianjin Medical University, Tianjin, PR China.

Department of Clinical Laboratory, Tianjin Academy of Traditional Chinese Medicine Affiliated Hospital, Tianjin, PR China.

出版信息

Parasitology. 2025 Feb;152(2):143-148. doi: 10.1017/S0031182025000113.

Abstract

Scabies is a neglected tropical disease caused by the ectoparasitic mite, var. (). Common scabies, the most prevalent clinical subtype of scabies, is characterized by pruritus, multiple skin lesions and low mite burden. In contrast, crusted scabies, an extremely contagious variant, is characterized by hyperkeratosis and high mite burden, with or without pruritus. Scabies can be diagnosed based on clinical manifestations, with confirmation obtained through microscopic identification of diagnostic features of . However, owing to the diversity and non-specific nature of its clinical manifestations and insufficient knowledge regarding early-stage clinical manifestations, the diagnosis of crusted scabies continues to be delayed. Herein, we present three cases of scabies with varying degrees of crusting and mite burden. Three patients with physical and microscopic results suggesting scabies were selected for this study. Case 1 had mild crusting and low mite burden, case 2 had severe crusting and high mite burden and case 3 had mild crusting and high mite burden. In this case report, 'the initial stage of crusted scabies' refers to the progression from common to crusted scabies. The discussion regarding the diagnostic characteristics of the initial stage of crusted scabies is expected to aid the early diagnosis of crusted scabies.

摘要

疥疮是一种由体外寄生螨()引起的被忽视的热带病。普通疥疮是疥疮最常见的临床亚型,其特征为瘙痒、多处皮肤损害以及较低的螨虫负荷。相比之下,结痂性疥疮是一种极具传染性的变种,其特征为角化过度和较高的螨虫负荷,伴或不伴有瘙痒。疥疮可根据临床表现进行诊断,并通过显微镜鉴定()的诊断特征来确诊。然而,由于其临床表现的多样性和非特异性,以及对早期临床表现的了解不足,结痂性疥疮的诊断仍然存在延迟。在此,我们报告三例具有不同程度结痂和螨虫负荷的疥疮病例。选择了三名体格检查和显微镜检查结果提示患有疥疮的患者进行本研究。病例1结痂较轻且螨虫负荷较低,病例2结痂严重且螨虫负荷较高,病例3结痂较轻但螨虫负荷较高。在本病例报告中,“结痂性疥疮的初期”指的是从普通疥疮发展为结痂性疥疮的过程。对结痂性疥疮初期诊断特征的讨论有望有助于结痂性疥疮的早期诊断。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/5993/12089439/2cd3dd48584a/S0031182025000113_figAb1.jpg

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