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《女性一生的骨骼健康》

'Bone Health-Across a Woman's Lifespan'.

作者信息

Stokes Gabrielle, Herath Madhuni, Samad Navira, Trinh Anne, Milat Frances

机构信息

Centre for Endocrinology & Metabolism, Hudson Institute of Medical Research, Clayton, Victoria, Australia.

Department of Medicine, School of Clinical Sciences, Monash University, Clayton, Victoria, Australia.

出版信息

Clin Endocrinol (Oxf). 2025 Apr;102(4):389-402. doi: 10.1111/cen.15203. Epub 2025 Jan 27.

DOI:10.1111/cen.15203
PMID:39871618
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11874200/
Abstract

Despite a high burden of osteoporosis and minimal trauma fractures worldwide, there is still a treatment gap in timely diagnosis and optimal treatment. There is also a lack of international consensus and guidelines on the management of bone fragility in premenopausal women. This review article provides an overview of the current understanding of factors impacting women's bone health across the adult lifespan, as well as dilemmas in the diagnosis, assessment and management of osteoporosis in premenopausal and postmenopausal women, premature ovarian insufficiency and bone health following breast cancer.

摘要

尽管全球骨质疏松症负担沉重且低创伤骨折发生率高,但在及时诊断和最佳治疗方面仍存在治疗差距。对于绝经前女性骨脆性管理,也缺乏国际共识和指南。这篇综述文章概述了目前对影响成年女性一生骨骼健康的因素的理解,以及绝经前和绝经后女性骨质疏松症、卵巢早衰及乳腺癌后骨骼健康在诊断、评估和管理方面的困境。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bf1/11874200/f68c8e8f2e83/CEN-102-389-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bf1/11874200/8748d14e28fe/CEN-102-389-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bf1/11874200/4bf9192601dd/CEN-102-389-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bf1/11874200/f7963ad3f107/CEN-102-389-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bf1/11874200/f68c8e8f2e83/CEN-102-389-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bf1/11874200/8748d14e28fe/CEN-102-389-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bf1/11874200/4bf9192601dd/CEN-102-389-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bf1/11874200/f7963ad3f107/CEN-102-389-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8bf1/11874200/f68c8e8f2e83/CEN-102-389-g002.jpg

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1
'Bone Health-Across a Woman's Lifespan'.《女性一生的骨骼健康》
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引用本文的文献

1
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Curr Oncol. 2025 May 26;32(6):305. doi: 10.3390/curroncol32060305.

本文引用的文献

1
Bone health in women with premature ovarian insufficiency/early menopause: a 23-year longitudinal analysis.早发性卵巢功能不全/早绝经女性的骨骼健康:23 年的纵向分析。
Hum Reprod. 2024 May 2;39(5):1013-1022. doi: 10.1093/humrep/deae037.
2
Femora of women with premature ovarian insufficiency exhibit reduced strength and misalignment with the transmitted vertical forces from the upper body.卵巢早衰女性的股骨表现出强度降低以及与上身传递的垂直力方向不一致。
Eur J Endocrinol. 2024 Feb 1;190(2):182-191. doi: 10.1093/ejendo/lvad158.
3
Effect of a Three-Day Course of Dexamethasone on Acute Phase Response Following Treatment With Zoledronate: A Randomized Controlled Trial.
地塞米松三日疗程对唑来膦酸治疗后急性期反应的影响:一项随机对照试验。
J Bone Miner Res. 2023 May;38(5):631-638. doi: 10.1002/jbmr.4802. Epub 2023 Apr 9.
4
Is It Time to Reconsider the U.S. Recommendations for Dietary Protein and Amino Acid Intake?是否到了重新考虑美国膳食蛋白质和氨基酸摄入量建议的时候了?
Nutrients. 2023 Feb 6;15(4):838. doi: 10.3390/nu15040838.
5
Impact of hormone therapy on the bone density of women with premature ovarian insufficiency: A systematic review.激素治疗对早发性卵巢功能不全女性骨密度的影响:系统评价。
Maturitas. 2023 Jan;167:105-112. doi: 10.1016/j.maturitas.2022.09.011. Epub 2022 Oct 14.
6
Abnormal Trabecular Bone Score, Lower Bone Mineral Density and Lean Mass in Young Women With Premature Ovarian Insufficiency Are Prevented by Oestrogen Replacement.年轻的卵巢早衰女性中,异常的骨小梁骨评分、较低的骨密度和瘦体重可以通过雌激素替代治疗预防。
Front Endocrinol (Lausanne). 2022 May 19;13:860853. doi: 10.3389/fendo.2022.860853. eCollection 2022.
7
Risedronate for the primary and secondary prevention of osteoporotic fractures in postmenopausal women.利塞膦酸钠用于绝经后妇女骨质疏松性骨折的一级和二级预防。
Cochrane Database Syst Rev. 2022 May 3;5(5):CD004523. doi: 10.1002/14651858.CD004523.pub4.
8
The clinician's guide to prevention and treatment of osteoporosis.临床医生骨质疏松症防治指南。
Osteoporos Int. 2022 Oct;33(10):2049-2102. doi: 10.1007/s00198-021-05900-y. Epub 2022 Apr 28.
9
UK clinical guideline for the prevention and treatment of osteoporosis.英国临床骨质疏松症预防和治疗指南。
Arch Osteoporos. 2022 Apr 5;17(1):58. doi: 10.1007/s11657-022-01061-5.
10
Association between parity and bone mineral density in postmenopausal women.绝经后妇女的生育次数与骨密度之间的关系。
BMC Womens Health. 2022 Mar 23;22(1):87. doi: 10.1186/s12905-022-01662-9.