Jonsson Kristoffer, Routier-Kierzkowska Anne-Lise, Bhalerao Rishikesh P
Department of Biological Sciences, IRBV, University of Montreal, 4101 Sherbrooke Est, Montreal, QC, H1X 2B2, Canada.
Department of Forest Genetics and Plant Physiology, Umeå Plant Science Centre (UPSC), Swedish University of Agricultural Sciences, 901 83, Umeå, Sweden.
New Phytol. 2025 Mar;245(6):2422-2427. doi: 10.1111/nph.20413. Epub 2025 Jan 28.
Plant development depends on growth asymmetry to establish body plans and adapt to environmental stimuli. We explore how plants initiate, propagate, and regulate organ-wide growth asymmetries. External cues, such as light and gravity, and internal signals, including stochastic cellular growth variability, drive these asymmetries. The plant hormone auxin orchestrates growth asymmetry through its distribution and transport. Mechanochemical feedback loops, exemplified by apical hook formation, further amplify growth asymmetries, illustrating the dynamic interplay between biochemical signals and physical forces. Growth asymmetry itself can serve as a continuous cue, influencing subsequent growth decisions. By examining specific cellular programs and their responses to asymmetric cues, we propose that the decision to either amplify or dampen these asymmetries is key to shaping plant organs.
植物发育依赖于生长不对称性来建立身体结构并适应环境刺激。我们探究植物如何启动、传播和调节全器官的生长不对称性。外部线索，如光和重力，以及内部信号，包括随机的细胞生长变异性，驱动着这些不对称性。植物激素生长素通过其分布和运输来协调生长不对称性。以顶端弯钩形成为例的机械化学反馈回路进一步放大了生长不对称性，说明了生化信号与物理力之间的动态相互作用。生长不对称性本身可以作为一个持续的线索，影响后续的生长决策。通过研究特定的细胞程序及其对不对称线索的反应，我们提出，放大或抑制这些不对称性的决定是塑造植物器官的关键。
