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[F]氟代脱氧葡萄糖正电子发射断层扫描/计算机断层扫描与[F]氟代脱氧葡萄糖正电子发射断层扫描/磁共振成像在非小细胞肺癌分期中的应用：一项直接比较的荟萃分析。

[F]FDG PET/CT versus [F]FDG PET/MRI in staging of non-small cell lung cancer: a head-to-head comparative meta-analysis.

作者信息

Yu Dandan, Chen Chaolin

机构信息

Department of Clinical Pharmacy, Traditional Chinese Medical Hospital of Zhuji, Shaoxing, China.

出版信息

Front Med (Lausanne). 2025 Jan 13;11:1517805. doi: 10.3389/fmed.2024.1517805. eCollection 2024.

DOI:10.3389/fmed.2024.1517805
PMID:39871837
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11769939/
Abstract

PURPOSE

This meta-analysis aims to compare the diagnostic efficacy of [F]FDG PET/CT and [F]FDG PET/MRI in patients with non-small cell lung cancer (NSCLC).

METHODS

An extensive literature search was conducted throughout the PubMed, Embase, and Web of Science databases for works accessible through September 2024. We included studies assessed the diagnostic efficacy of [F]FDG PET/CT and [F]FDG PET/MRI in NSCLC.

RESULTS

The meta-analysis includes six studies with a total of 437 patients. The sensitivity and specificity of [F]FDG PET/CT and [F]FDG PET/MRI for detecting lymph node metastasis were similar, at 0.82 (0.68-0.94) vs. 0.86 (0.70-0.97) and 0.88 (0.76-0.96) vs. 0.90 (0.85-0.94), respectively, with no significant differences ( = 0.70 for sensitivity,  = 0.75 for specificity). For distant metastasis, the sensitivity of [F]FDG PET/CT and [F]FDG PET/MRI was 0.86 (0.60-1.00) and 0.93 (0.63-1.00), and specificity was 0.89 (0.65-1.00) vs. 0.90 (0.64-1.00), respectively, also showing no significant differences ( = 0.66 for sensitivity,  = 0.97 for specificity).

CONCLUSION

Our meta-analysis shows that [F]FDG PET/MRI has similar sensitivity and specificity to [F]FDG PET/CT in identifying lymph node and distant metastases in patients with NSCLC. Additional larger sample prospective studies are needed to confirm these findings.

SYSTEMATIC REVIEW REGISTRATION

https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023479817, CRD42023479817.

摘要

目的

本荟萃分析旨在比较[F]FDG PET/CT和[F]FDG PET/MRI在非小细胞肺癌（NSCLC）患者中的诊断效能。

方法

通过PubMed、Embase和Web of Science数据库进行全面的文献检索，查找截至2024年9月可获取的研究。我们纳入了评估[F]FDG PET/CT和[F]FDG PET/MRI在NSCLC中诊断效能的研究。

结果

该荟萃分析纳入了6项研究，共437例患者。[F]FDG PET/CT和[F]FDG PET/MRI检测淋巴结转移的敏感性和特异性相似，分别为0.82（0.68 - 0.94）对0.86（0.70 - 0.97）以及0.88（0.76 - 0.96）对0.90（0.85 - 0.94），差异无统计学意义（敏感性 = 0.70，特异性 = 0.75）。对于远处转移，[F]FDG PET/CT和[F]FDG PET/MRI的敏感性分别为0.86（0.60 - 1.00）和0.93（0.63 - 1.00），特异性分别为0.89（0.65 - 1.00）对0.90（0.64 - 1.00），同样差异无统计学意义（敏感性 = 0.66，特异性 = 0.97）。

结论

我们的荟萃分析表明，[F]FDG PET/MRI在识别NSCLC患者的淋巴结和远处转移方面，与[F]FDG PET/CT具有相似的敏感性和特异性。需要更多更大样本的前瞻性研究来证实这些发现。

系统评价注册

https://www.crd.york.ac.uk/prospero/display_record.php?ID=CRD42023479817，CRD42023479817。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab54/11769939/22f97e74a398/fmed-11-1517805-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab54/11769939/be40cc2a25e0/fmed-11-1517805-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab54/11769939/8cc272e68e86/fmed-11-1517805-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab54/11769939/dd24f4025d20/fmed-11-1517805-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab54/11769939/546a485598a6/fmed-11-1517805-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab54/11769939/0d58c9afd702/fmed-11-1517805-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab54/11769939/22f97e74a398/fmed-11-1517805-g006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab54/11769939/be40cc2a25e0/fmed-11-1517805-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab54/11769939/8cc272e68e86/fmed-11-1517805-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab54/11769939/dd24f4025d20/fmed-11-1517805-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab54/11769939/546a485598a6/fmed-11-1517805-g004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab54/11769939/0d58c9afd702/fmed-11-1517805-g005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/ab54/11769939/22f97e74a398/fmed-11-1517805-g006.jpg

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本文引用的文献

1
Non-small-cell lung cancer.非小细胞肺癌。
Nat Rev Dis Primers. 2024 Sep 26;10(1):71. doi: 10.1038/s41572-024-00551-9.
2
Non-Small Cell Lung Cancer, Version 4.2024, NCCN Clinical Practice Guidelines in Oncology.非小细胞肺癌临床实践指南（第 4.2024 版），NCCN 肿瘤学临床实践指南
J Natl Compr Canc Netw. 2024 May;22(4):249-274. doi: 10.6004/jnccn.2204.0023.
3
Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries.2022 年全球癌症统计数据：全球 185 个国家和地区 36 种癌症的发病率和死亡率全球估计数。
CA Cancer J Clin. 2024 May-Jun;74(3):229-263. doi: 10.3322/caac.21834. Epub 2024 Apr 4.
4
Head-to-head comparison of F-FDG PET/CT and F-FDG PET/MRI for lymph node metastasis staging in non-small cell lung cancer: a meta-analysis.头对头比较 F-FDG PET/CT 和 F-FDG PET/MRI 在非小细胞肺癌淋巴结转移分期中的应用：一项荟萃分析。
Diagn Interv Radiol. 2024 Mar 6;30(2):99-106. doi: 10.4274/dir.2023.232280. Epub 2024 Jan 31.
5
Observed and relative survival trends of lung cancer: A systematic review of population-based cancer registration data.肺癌观察生存率和相对生存率趋势：基于人群的癌症登记数据的系统评价。
Thorac Cancer. 2024 Jan;15(2):142-151. doi: 10.1111/1759-7714.15170. Epub 2023 Nov 20.
6
Systematic Review of Lung Cancer Screening: Advancements and Strategies for Implementation.肺癌筛查的系统评价：进展与实施策略
Healthcare (Basel). 2023 Jul 21;11(14):2085. doi: 10.3390/healthcare11142085.
7
The lung cancers: staging and response, CT, F-FDG PET/CT, MRI, DWI: review and new perspectives.肺癌的分期和疗效评价：CT、F-FDG PET/CT、MRI、DWI——综述及新视角
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8
Global burden and trends of lung cancer incidence and mortality.全球肺癌发病率和死亡率的负担及趋势。
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9
Comparative evaluation of PD-L1 expression in cytology imprints, circulating tumour cells and tumour tissue in non-small cell lung cancer patients.比较细胞学印片、循环肿瘤细胞与非小细胞肺癌患者肿瘤组织中 PD-L1 表达的评估。
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10
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BMC Cancer. 2023 Jan 10;23(1):37. doi: 10.1186/s12885-022-10493-8.