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因纽特人中的伊尔斯病:简短报告及临床进展

Eales' Disease in Inuit: A Short Report and Clinical Update.

作者信息

Forshaw Thomas Richard Johansen, Moldow Birgitte

机构信息

Department of Ophthalmology, Rigshospitalet-Glostrup, Glostrup, Denmark.

Department of Ophthalmology, Sygehus Sønderjylland, Sønderborg, Denmark.

出版信息

Int Med Case Rep J. 2025 Jan 23;18:157-161. doi: 10.2147/IMCRJ.S505170. eCollection 2025.

Abstract

PURPOSE

We report a case of Eales disease in Inuit and reflect on advances in telemedicine and treatment of retinal disease since the first report of Eales' disease in Greenlandic Inuit was published.

PATIENTS AND METHODS

A 41-year-old Inuit female complaining of blurred vision was referred to our eye department. There had been no sign of diabetic retinopathy during diabetic eye screening and the patient had been treated for tuberculosis in 2010. Telemedical assessment was suspicious for vitritis or vitreous hemorrhage in the right eye, and the patient was flown from Greenland to Denmark, where examination revealed mild vitritis in the right eye, vitreous hemorrhage in the left eye and retinal neovascularization in both eyes. Fundus fluorescein angiography showed vessel leakage and areas of retinal non-perfusion. There was left epiretinal membrane with retinal thickening on macular optical coherence tomography.

RESULTS

Based on the patient's clinical findings and history of tuberculosis infection, a diagnosis of Eales' disease was made. The left eye was treated with pars plana vitrectomy with epiretinal membrane peeling, endodiathermy and endolaser. The right eye was treated in outpatients with sectoral laser photocoagulation. At seven weeks' follow-up, the visual acuity had improved from 6/12 to 6/6 (right eye) and from 6/36 to 6/7.5 (left eye).

CONCLUSION

The prevalence of tuberculosis in Greenland is very high and it is recommended that clinicians remain alert to the possibility of Eales' disease, as beneficial visual outcomes are associated with prompt diagnosis and treatment. Telemedicine allows more frequent follow-up of Greenlander patients.

摘要

目的

我们报告一例因纽特人患伊尔斯病的病例,并回顾自格陵兰因纽特人伊尔斯病首次报告发表以来远程医疗和视网膜疾病治疗方面的进展。

患者与方法

一名41岁抱怨视力模糊的因纽特女性被转诊至我们眼科。糖尿病眼部筛查期间未发现糖尿病视网膜病变迹象,该患者曾在2010年接受过结核病治疗。远程医疗评估怀疑右眼有玻璃体炎或玻璃体积血,患者从格陵兰被空运至丹麦,在丹麦检查发现右眼有轻度玻璃体炎,左眼有玻璃体积血,双眼均有视网膜新生血管形成。眼底荧光血管造影显示血管渗漏和视网膜无灌注区。黄斑光学相干断层扫描显示左眼有视网膜前膜伴视网膜增厚。

结果

根据患者的临床表现和结核感染病史,诊断为伊尔斯病。左眼行玻璃体切除术,联合视网膜前膜剥除、眼内透热疗法和眼内激光光凝术。右眼在门诊接受扇形激光光凝治疗。随访7周时,视力从6/12提高到6/6(右眼),从6/36提高到6/7.5(左眼)。

结论

格陵兰结核病患病率非常高,建议临床医生对伊尔斯病的可能性保持警惕,因为及时诊断和治疗可带来有益的视力预后。远程医疗使格陵兰患者能更频繁地接受随访。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/24d6/11771164/defa438df37a/IMCRJ-18-157-g0001.jpg

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