İstanbul Retina Institute, İstanbul, Turkey
Turk J Ophthalmol. 2021 Apr 29;51(2):102-106. doi: 10.4274/tjo.galenos.2020.43709.
To investigate visual and anatomical outcomes of vitreoretinal surgeries in patients with Eales' disease.
In this retrospective study, 22 eyes of 21 patients with vitreous hemorrhage (VH) or tractional retinal detachment (TRD) secondary to Eales' disease who underwent vitreoretinal surgery between January 1997 and December 2015 and had at least 1 year of follow-up were included.
The mean best corrected visual acuity (BCVA) was significantly higher at final visit (0.6±0.9 logMAR) than the preoperative values (1.8±1.1 logMAR) (p<0.001). After surgery, BCVA was stable in 4 eyes (18.2%), increased in 16 eyes (72.7%), and decreased in 2 eyes (9.1%). Although the mean BCVA was better in the VH group (0.3±0.34 logMAR) than the TRD group (0.9±1.1 logMAR), the difference was not statistically significant (p=0.1). Multivariable linear regression analyses revealed that final BCVA was negatively associated with preoperative or postoperative proliferative vitreoretinopathy grade C (PVR-C), preoperative retinal detachment involving the macula, postoperative neovascular glaucoma, and long preoperative duration of disease, and positively associated with preoperative BCVA. Final BCVA was not associated with preoperative retinal and disc neovascularization, rubeosis iridis, total posterior hyaloid detachment, preoperative retinal laser photocoagulation, indication of surgery, diameter of sclerotomy (20 or 23 gauge), preoperative lens status, preoperative or postoperative epimacular membrane, peroperative iatrogenic retinal breaks, postoperative hypotony, cystoid macular edema, and new or recurrent retinal detachment. The primary anatomic success rate was 81.8% and the final anatomic success rate was 90.9%.
In Eales' disease, good visual results can be obtained with vitreoretinal surgery if the detachment area does not involve the macula and PVR-C does not develop pre- or postoperatively.
研究眼后段疾病导致的 Eales 病患者行玻璃体视网膜手术后的视力和解剖学结果。
本回顾性研究纳入了 1997 年 1 月至 2015 年 12 月期间因 Eales 病所致玻璃体积血（VH）或牵拉性视网膜脱离（TRD）而行玻璃体视网膜手术且至少随访 1 年的 21 例 22 只眼。
最终随访时最佳矫正视力（BCVA）均值（0.6±0.9 logMAR）显著高于术前（1.8±1.1 logMAR）（p<0.001）。术后，4 只眼（18.2%）的 BCVA 稳定，16 只眼（72.7%）的 BCVA 提高，2 只眼（9.1%）的 BCVA 下降。尽管 VH 组的平均 BCVA（0.3±0.34 logMAR）优于 TRD 组（0.9±1.1 logMAR），但差异无统计学意义（p=0.1）。多变量线性回归分析显示，最终 BCVA 与术前或术后增生性玻璃体视网膜病变 C 级（PVR-C）、术前累及黄斑的视网膜脱离、术后新生血管性青光眼以及较长的术前病程呈负相关，与术前 BCVA 呈正相关。最终 BCVA 与术前视网膜和视盘新生血管、虹膜新生血管、完全后玻璃体脱离、术前视网膜激光光凝、手术适应证、巩膜切口（20 或 23 号）直径、术前晶状体状态、术前或术后黄斑前膜、术中医源性视网膜裂孔、术后低眼压、黄斑囊样水肿以及新发性或复发性视网膜脱离无关。主要解剖学成功率为 81.8%，最终解剖学成功率为 90.9%。
如果脱离区不累及黄斑且术前或术后无 PVR-C 发生，Eales 病患者行玻璃体视网膜手术后可获得良好的视力结果。
