精氨酸在肝癌中的代谢信号传导作用。 - Suppr

Suppr

超能文献

A metabolic signalling role for arginine in liver cancer.

作者信息

Sokolov David, Sullivan Lucas B

机构信息

Human Biology Division, Fred Hutchinson Cancer Center, Seattle, WA 98109, United States.

出版信息

Life Metab. 2023 Nov 27;3(1):load046. doi: 10.1093/lifemeta/load046. eCollection 2024 Feb.

DOI:10.1093/lifemeta/load046

PMID:39871876

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11752401/

Abstract

摘要

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f15f/11752401/7e51d202516c/load046_fig1.jpg

相似文献

A metabolic signalling role for arginine in liver cancer.

Life Metab. 2023 Nov 27;3(1):load046. doi: 10.1093/lifemeta/load046. eCollection 2024 Feb.

Interaction of N-acetyl-l-glutamate kinase with the PII signal transducer in the non-photosynthetic alga Polytomella parva: Co-evolution towards a hetero-oligomeric enzyme.

FEBS J. 2020 Feb;287(3):465-482. doi: 10.1111/febs.14989. Epub 2019 Jul 26.

Targeting RNA-binding motif protein 39 for arginine reduction: unveiling metabolic vulnerability in arginine-dependent liver cancer.

MedComm (2020). 2024 Jun 19;5(7):e581. doi: 10.1002/mco2.581. eCollection 2024 Jul.

Role of protein arginine methyltransferase 1 in obesity-related metabolic disorders: Research progress and implications.

Diabetes Obes Metab. 2024 Sep;26(9):3491-3500. doi: 10.1111/dom.15640. Epub 2024 May 15.

Adipose type I interferon signalling protects against metabolic dysfunction.

Gut. 2018 Jan;67(1):157-165. doi: 10.1136/gutjnl-2016-313155. Epub 2016 Dec 23.

Epigenetic arginine methylation in breast cancer: emerging therapeutic strategies.

J Mol Endocrinol. 2019 Apr 1;62(3):R223-R237. doi: 10.1530/JME-18-0224.

Accumulation of 8-hydroxydeoxyguanosine, L-arginine and Glucose Metabolites by Liver Tumor Cells Are the Important Characteristic Features of Metabolic Syndrome and Non-Alcoholic Steatohepatitis-Associated Hepatocarcinogenesis.

Int J Mol Sci. 2020 Oct 20;21(20):7746. doi: 10.3390/ijms21207746.

Metabolic fate of extrahepatic arginine in liver after burn injury.

Metabolism. 2003 Oct;52(10):1232-9. doi: 10.1016/s0026-0495(03)00282-8.

Chronic l-arginine treatment improves metabolic, cardiovascular and liver complications in diet-induced obesity in rats.

Food Funct. 2013 Jan;4(1):83-91. doi: 10.1039/c2fo30096f. Epub 2012 Sep 25.

Alterations in arginine and energy metabolism, structural and signalling lipids in metastatic breast cancer in mice detected in plasma by targeted metabolomics and lipidomics.

Breast Cancer Res. 2018 Dec 4;20(1):148. doi: 10.1186/s13058-018-1075-y.

引用本文的文献

D-ribose-5-phosphate inactivates YAP and functions as a metabolic checkpoint.

J Hematol Oncol. 2025 Jan 4;18(1):2. doi: 10.1186/s13045-024-01655-1.

本文引用的文献

Arginine reprograms metabolism in liver cancer via RBM39.

Cell. 2023 Nov 9;186(23):5068-5083.e23. doi: 10.1016/j.cell.2023.09.011. Epub 2023 Oct 6.

GCN2 inhibition sensitizes arginine-deprived hepatocellular carcinoma cells to senolytic treatment.

Cell Metab. 2022 Aug 2;34(8):1151-1167.e7. doi: 10.1016/j.cmet.2022.06.010. Epub 2022 Jul 14.

The context-specific roles of urea cycle enzymes in tumorigenesis.

Mol Cell. 2021 Sep 16;81(18):3749-3759. doi: 10.1016/j.molcel.2021.08.005. Epub 2021 Aug 31.

Multi-omics data integration reveals novel drug targets in hepatocellular carcinoma.

BMC Genomics. 2021 Aug 4;22(1):592. doi: 10.1186/s12864-021-07876-9.

Metabolism and function of polyamines in cancer progression.

Cancer Lett. 2021 Oct 28;519:91-104. doi: 10.1016/j.canlet.2021.06.020. Epub 2021 Jun 27.

RNA-binding motif protein 39 (RBM39): An emerging cancer target.

Br J Pharmacol. 2022 Jun;179(12):2795-2812. doi: 10.1111/bph.15331. Epub 2021 Jan 3.

Anticancer sulfonamides target splicing by inducing RBM39 degradation via recruitment to DCAF15.

Science. 2017 Apr 28;356(6336). doi: 10.1126/science.aal3755. Epub 2017 Mar 16.

L-Arginine Modulates T Cell Metabolism and Enhances Survival and Anti-tumor Activity.

Cell. 2016 Oct 20;167(3):829-842.e13. doi: 10.1016/j.cell.2016.09.031. Epub 2016 Oct 13.

Mechanism of arginine sensing by CASTOR1 upstream of mTORC1.

Nature. 2016 Aug 11;536(7615):229-33. doi: 10.1038/nature19079. Epub 2016 Aug 3.

Targeting arginine metabolism pathway to treat arginine-dependent cancers.

Cancer Lett. 2015 Aug 1;364(1):1-7. doi: 10.1016/j.canlet.2015.04.020. Epub 2015 Apr 23.

文献AI研究员

20分钟写一篇综述，助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型，支持多种主流文档格式。

立即体验