• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

Transcript profile of gene in human white adipose tissue is associated with obesity and mitochondrial gene program.

作者信息

Bai Ningning, Lu Xuhong, Wang Yansu, Li Xiaoya, Zhang Rong, Yu Haoyong, Hu Cheng, Ma Xiaojing, Bao Yuqian, Yang Ying

机构信息

Department of Endocrinology and Metabolism, Shanghai Diabetes Institute, Shanghai Clinical Center for Diabetes, Shanghai Key Laboratory of Diabetes Mellitus, Shanghai Key Clinical Center for Metabolic Disease, Shanghai Jiao Tong University School of Medicine Affiliated Sixth People's Hospital, Shanghai 200233, China.

Department of Endocrinology, Shenzhen Second People's Hospital, the First Affiliated Hospital of Shenzhen University, Health Science Center of Shenzhen University, Shenzhen Clinical Research Center for Metabolic Diseases, Shenzhen Center for Diabetes Control and Prevention, Shenzhen, Guangdong 518000, China.

出版信息

Life Metab. 2023 Sep 14;2(6):load037. doi: 10.1093/lifemeta/load037. eCollection 2023 Dec.

DOI:10.1093/lifemeta/load037
PMID:39872858
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11748976/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6548/11748976/ff14db010394/load037_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6548/11748976/ff14db010394/load037_fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6548/11748976/ff14db010394/load037_fig1.jpg

相似文献

1
Transcript profile of gene in human white adipose tissue is associated with obesity and mitochondrial gene program.人类白色脂肪组织中基因的转录谱与肥胖和线粒体基因程序相关。
Life Metab. 2023 Sep 14;2(6):load037. doi: 10.1093/lifemeta/load037. eCollection 2023 Dec.
2
Adipose-specific gene associates with human obesity.脂肪特异性基因与人类肥胖相关。
Metabol Open. 2024 Jan 2;22:100269. doi: 10.1016/j.metop.2024.100269. eCollection 2024 Jun.
3
Dysregulated adipose tissue expansion and impaired adipogenesis in Prader-Willi syndrome children before obesity-onset.普瑞德威利综合征儿童肥胖前脂肪组织过度扩张和脂肪生成受损。
Metabolism. 2022 Nov;136:155295. doi: 10.1016/j.metabol.2022.155295. Epub 2022 Aug 22.
4
White adipose tissue mitochondrial metabolism in health and in obesity.健康与肥胖状态下白色脂肪组织线粒体代谢。
Obes Rev. 2020 Feb;21(2):e12958. doi: 10.1111/obr.12958. Epub 2019 Nov 27.
5
Physical training, UCP1 expression, mitochondrial density, and coupling in adipose tissue from women with obesity.肥胖女性脂肪组织的体能训练、UCP1 表达、线粒体密度和偶联
Scand J Med Sci Sports. 2019 Nov;29(11):1699-1706. doi: 10.1111/sms.13514. Epub 2019 Jul 22.
6
Nutrition modulates Fto and Irx3 gene transcript levels, but does not alter their DNA methylation profiles in rat white adipose tissues.营养调节大鼠白色脂肪组织中Fto和Irx3基因的转录水平，但不改变其DNA甲基化谱。
Gene. 2017 Apr 30;610:44-48. doi: 10.1016/j.gene.2017.02.002. Epub 2017 Feb 5.
7
CLSTN3 gene variant associates with obesity risk and contributes to dysfunction in white adipose tissue.CLSTN3 基因变异与肥胖风险相关，并导致白色脂肪组织功能障碍。
Mol Metab. 2022 Sep;63:101531. doi: 10.1016/j.molmet.2022.101531. Epub 2022 Jun 24.
8
White adipose tissue mitochondrial bioenergetics in metabolic diseases.代谢性疾病中的白色脂肪组织线粒体生物能学。
Rev Endocr Metab Disord. 2023 Dec;24(6):1121-1133. doi: 10.1007/s11154-023-09827-z. Epub 2023 Aug 10.
9
Melatonin improves mitochondrial function in inguinal white adipose tissue of Zücker diabetic fatty rats.褪黑素改善 Zücker 糖尿病肥胖大鼠腹股沟白色脂肪组织中线粒体功能。
J Pineal Res. 2014 Aug;57(1):103-9. doi: 10.1111/jpi.12147. Epub 2014 Jul 10.
10
LMO3 reprograms visceral adipocyte metabolism during obesity.LMO3 重编程肥胖过程中内脏脂肪细胞的代谢。
J Mol Med (Berl). 2021 Aug;99(8):1151-1171. doi: 10.1007/s00109-021-02089-9. Epub 2021 May 20.

引用本文的文献

1
PPARα regulates ER-lipid droplet protein Calsyntenin-3β to promote ketogenesis in hepatocytes.过氧化物酶体增殖物激活受体α（PPARα）调节内质网-脂滴蛋白钙黏连蛋白-3β，以促进肝细胞中的生酮作用。
Proc Natl Acad Sci U S A. 2025 Apr 29;122(17):e2426338122. doi: 10.1073/pnas.2426338122. Epub 2025 Apr 21.
2
Long-Term Dietary Consumption of Grapes Alters Phenotypic Expression in Skeletal Muscle of Aged Male and Female Mice.长期食用葡萄会改变老年雄性和雌性小鼠骨骼肌的表型表达。
Foods. 2025 Feb 18;14(4):695. doi: 10.3390/foods14040695.

本文引用的文献

1
CLSTN3β enforces adipocyte multilocularity to facilitate lipid utilization.CLSTN3β 增强脂肪细胞的多房性以促进脂质利用。
Nature. 2023 Jan;613(7942):160-168. doi: 10.1038/s41586-022-05507-1. Epub 2022 Dec 7.
2
CLSTN3 gene variant associates with obesity risk and contributes to dysfunction in white adipose tissue.CLSTN3 基因变异与肥胖风险相关，并导致白色脂肪组织功能障碍。
Mol Metab. 2022 Sep;63:101531. doi: 10.1016/j.molmet.2022.101531. Epub 2022 Jun 24.
3
A single-cell atlas of human and mouse white adipose tissue.人类和小鼠白色脂肪组织的单细胞图谱
Nature. 2022 Mar;603(7903):926-933. doi: 10.1038/s41586-022-04518-2. Epub 2022 Mar 16.
4
Seipin localizes at endoplasmic-reticulum-mitochondria contact sites to control mitochondrial calcium import and metabolism in adipocytes.Seipin 定位于内质网-线粒体接触位点，以控制脂肪细胞中线粒体的钙摄取和代谢。
Cell Rep. 2022 Jan 11;38(2):110213. doi: 10.1016/j.celrep.2021.110213.
5
Proteomic Signatures of Human Visceral and Subcutaneous Adipocytes.人类内脏和皮下脂肪细胞的蛋白质组学特征。
J Clin Endocrinol Metab. 2022 Feb 17;107(3):755-775. doi: 10.1210/clinem/dgab756.
6
Lipid and glucose metabolism in white adipocytes: pathways, dysfunction and therapeutics.白色脂肪细胞中的脂类和糖代谢：途径、功能障碍与治疗学。
Nat Rev Endocrinol. 2021 May;17(5):276-295. doi: 10.1038/s41574-021-00471-8. Epub 2021 Feb 24.
7
Innervation of thermogenic adipose tissue via a calsyntenin 3β-S100b axis.通过钙结合蛋白 3β-S100b 轴对产热脂肪组织的神经支配。
Nature. 2019 May;569(7755):229-235. doi: 10.1038/s41586-019-1156-9. Epub 2019 May 1.
8
Anatomical, Physiological, and Functional Diversity of Adipose Tissue.脂肪组织的解剖、生理和功能多样性。
Cell Metab. 2018 Jan 9;27(1):68-83. doi: 10.1016/j.cmet.2017.12.002.
9
The ominous triad of adipose tissue dysfunction: inflammation, fibrosis, and impaired angiogenesis.脂肪组织功能障碍的不祥三联征：炎症、纤维化和血管生成受损。
J Clin Invest. 2017 Jan 3;127(1):74-82. doi: 10.1172/JCI88883.
10
Type 2 diabetes mellitus.2 型糖尿病。
Nat Rev Dis Primers. 2015 Jul 23;1:15019. doi: 10.1038/nrdp.2015.19.