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暴发性心肌炎患者凝血功能障碍的成功管理:一例报告

Successful management of coagulation dysfunction in a patient with fulminant myocarditis: a case report.

作者信息

Dong Shanshan, Peng Qi, Lu Kai, Wei Qimei, Yang Jun

机构信息

Department of Clinical Laboratory, Wuhan Asia Heart Hospital, Wuhan, China.

Department of Cardiac Critical Care Medicine, Wuhan Asia Heart Hospital, Wuhan, China.

出版信息

Front Cardiovasc Med. 2025 Jan 13;11:1538728. doi: 10.3389/fcvm.2024.1538728. eCollection 2024.

Abstract

Fulminant myocarditis (FM) is an acute, diffuse inflammatory myocardial disease characterized by abrupt onset and extremely rapid progression. Patients typically exhibit haemodynamic abnormalities that may lead to respiratory failure, liver and renal failure, and subsequent coagulopathy. Collectively, these complications significantly increase the risk of early mortality. Currently, there is limited research on coagulation dysfunction associated with FM; therefore, achieving a rebalancing of the coagulation system is a challenge for successful treatment. We report a case of coagulation disorder secondary to FM, in which the patient recovered successfully and was discharged following comprehensive treatment and correction of coagulation function. By analyzing the etiology of this condition and emphasizing strategies for correcting coagulation disorders, we aim to provide valuable references for clinical diagnosis and management.

摘要

暴发性心肌炎(FM)是一种急性、弥漫性炎症性心肌疾病,其特点为起病急骤且进展极快。患者通常会出现血流动力学异常,这可能导致呼吸衰竭、肝肾功能衰竭以及随后的凝血病。这些并发症共同显著增加了早期死亡风险。目前,关于与FM相关的凝血功能障碍的研究有限;因此,实现凝血系统的重新平衡是成功治疗的一项挑战。我们报告一例继发于FM的凝血障碍病例,该患者经综合治疗及凝血功能纠正后成功康复并出院。通过分析该病症的病因并强调纠正凝血障碍的策略,我们旨在为临床诊断和管理提供有价值的参考。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c312/11769995/6a712c949181/fcvm-11-1538728-g001.jpg

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