V474I germline variant drives breast cancer metastasis.
作者信息
Wang Hai, Shao Zhiming
机构信息
Key Laboratory of Breast Cancer in Shanghai, Department of Breast Surgery, Fudan University Shanghai Cancer Center; Department of Oncology, Shanghai Medical College, Fudan University, Shanghai 200032, China.
出版信息
Life Metab. 2025 Jan 4;4(1):loae041. doi: 10.1093/lifemeta/loae041. eCollection 2025 Feb.
Abstract
摘要
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Metastasis.转移。
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Inhibition of PCSK9 potentiates immune checkpoint therapy for cancer.抑制 PCSK9 可增强癌症的免疫检查点治疗。
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Common germline variants of the human APOE gene modulate melanoma progression and survival.人类 APOE 基因的常见种系变异可调节黑色素瘤的进展和生存。
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Minimal functional driver gene heterogeneity among untreated metastases.未治疗转移灶中功能性驱动基因的最小异质性。
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PCSK9: a key modulator of cardiovascular health.PCSK9：心血管健康的关键调节因子。
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Convergent multi-miRNA targeting of ApoE drives LRP1/LRP8-dependent melanoma metastasis and angiogenesis.载脂蛋白 E 的汇聚性多 miRNA 靶向作用驱动 LRP1/LRP8 依赖性黑色素瘤转移和血管生成。
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Interactions between cancer stem cells and their niche govern metastatic colonization.癌症干细胞与其生态位之间的相互作用控制着转移定植。
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A genome-wide association study of prognosis in breast cancer.全基因组关联研究在乳腺癌预后中的应用。
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