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使用不同材料和技术对中重度牙齿磨损患者进行微创全口修复的临床效果:一项系统评价和荟萃分析

Clinical performance of minimally invasive full-mouth rehabilitation using different materials and techniques for patients with moderate to severe tooth wear: a systematic review and meta-analysis.

作者信息

Fan Jiayan, Wang Bingjie, Wang Lutao, Xu Bin, Wang Liang, Wang Chaoyang, Fu Baiping

机构信息

Department of Stomatology, Ningbo No.2 Hospital, Ningbo, 315000, China.

Department of Stomatology, The Affiliated People's Hospital of Ningbo University (Ningbo Yinzhou People's Hospital), Ningbo, 315000, China.

出版信息

Clin Oral Investig. 2025 Jan 28;29(2):96. doi: 10.1007/s00784-025-06181-z.

Abstract

OBJECTIVE

To evaluate short, mid and long-term clinical outcomes and patients' satisfaction of minimally invasive full-mouth rehabilitation using different materials and techniques for patients with moderate to severe tooth wear. Furthermore, materials were analyzed to identify their influences on clinical results.

MATERIALS AND METHODS

Search was conducted in PubMed, Cochrane Central Register of Controlled Trial, Embase, Web of science and Scopus until December 19, 2024. Randomized clinical trials (RCT), cohort studies and case series with at least mean period of 3 years were included. The revised Cochrane risk of bias tool, Newcastle-Ottawa scale and Joanna Briggs Institute Critical Appraisal were used to evaluate the quality of RCT, cohort studies and case series. Meta-analysis and Poisson regression were conducted.

RESULTS

Ten studies in this review included three case series, six cohort studies and one RCT with three low, six moderate risks and one some concerns. Annual failure rates (AFRs) and annual complication rates (ACRs) of direct composite restorations were 0-6.2% and 1.0%-4.2%, respectively. AFRs of indirect restorations were 0%-0.5%. Overall ACRs of indirect restorations fabricated by traditional indirect resin composites, polymer-infiltrated ceramic-network, resin nanoceramics and ceramics were at 1.6%-15.1%, 0.7%-4.8%, 0.5%-5.0% and 0.2%-1.1%, respectively. The estimated AFRs of direct composites, resin nanoceramics and ceramics were 0.64%, 0.13% and 0.04% respectively. Significantly lowest AFRs of ceramic was found after mid-term follow-up with incidence rate ratios of direct composites, resin nanoceramics and ceramics being 1: 0.68 (P = 0.60): 0.001 (P < 0.05). The estimated ACRs of the three materials were 2.16%, 2.14% and 0.62%. Overall AFRs of restorations using different techniques were 0%-0.5%. Overall ACRs of direct and indirect techniques were 1.1%-2.2% and 0.2%-4.8%, respectively. Overall ACRs of hybrid technique were 0.5% to 15.1%. Restoration fracture was the most predominant complication regardless of materials. High appreciation was expressed by patient reported outcomes measures.

CONCLUSIONS

Minimally invasive full-mouth rehabilitation for patients with moderate to severe tooth wear presented good clinical performance apart from traditional indirect resin composite used in posterior teeth.

CLINICAL RELEVANCE

Minimally invasive full-mouth rehabilitation should be strongly advocated for the patients with moderately and severely worn dentition.

摘要

目的

评估采用不同材料和技术对中重度牙齿磨损患者进行微创全口修复的短期、中期和长期临床疗效及患者满意度。此外,对材料进行分析以确定其对临床结果的影响。

材料与方法

在PubMed、Cochrane对照试验中央注册库、Embase、科学网和Scopus中进行检索,截至2024年12月19日。纳入至少平均为期3年的随机临床试验(RCT)、队列研究和病例系列。使用修订的Cochrane偏倚风险工具、纽卡斯尔-渥太华量表和乔安娜·布里格斯研究所批判性评价来评估RCT、队列研究和病例系列的质量。进行荟萃分析和泊松回归。

结果

本综述中的10项研究包括3个病例系列、6个队列研究和1个RCT,其中3项低风险、6项中度风险和1项存在一些问题。直接复合树脂修复体的年失败率(AFR)和年并发症率(ACR)分别为0%-6.2%和1.0%-4.2%。间接修复体的AFR为0%-0.5%。传统间接树脂复合材料制成的间接修复体、聚合物渗透陶瓷网络、树脂纳米陶瓷和陶瓷的总体ACR分别为1.6%-15.1%、0.7%-4.8%、0.5%-5.0%和0.2%-1.1%。直接复合材料、树脂纳米陶瓷和陶瓷的估计AFR分别为0.6�%、0.13%和0.04%。中期随访后发现陶瓷的AFR显著最低,直接复合材料、树脂纳米陶瓷和陶瓷的发病率比为1:0.68(P = 0.60):0.001(P < 0.05)。这三种材料的估计ACR分别为2.16%、2.14%和0.62%。使用不同技术的修复体总体AFR为0%-0.5%。直接和间接技术的总体ACR分别为1.1%-2.2%和0.2%-4.8%。混合技术的总体ACR为0.5%至15.1%。无论材料如何,修复体断裂都是最主要的并发症。患者报告结局指标显示出高度认可。

结论

除了用于后牙的传统间接树脂复合材料外,中重度牙齿磨损患者的微创全口修复具有良好的临床性能。

临床意义

对于中度和重度牙列磨损患者,应大力提倡微创全口修复。

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