Ulberth Franz, Koeber Robert
Joint Research Centre, European Commission, 2440, Geel, Belgium.
Anal Bioanal Chem. 2025 May;417(12):2427-2438. doi: 10.1007/s00216-025-05743-0. Epub 2025 Jan 29.
The global food industry faces significant challenges in ensuring the safety and authenticity of food products. Economic adulteration and counterfeiting of food are estimated to cost the industry US$30-40 billion annually. Analytical testing plays a vital role in detecting food fraud. For ensuring the metrological traceability and comparability of testing results, the use of reference materials (RMs) is crucial. The article describes the role of RMs in food authenticity testing, including their applications in method validation, calibration, quality control, and the definition of conventional measurement scales. It also reviews the availability of RMs that can be used in measurement procedures to authenticate food. Furthermore, the applications of RMs in targeted adulterant detection methods, for compositional parameters used to authenticate foods and food supplements, isotopic measurements, untargeted food authenticity testing methods, and detection and quantification of genetically modified organisms (GMOs), are explored. The document concludes by recommending the development of research grade test materials or representative test materials to harmonise untargeted testing methods and improve comparability of results across laboratories and over time.
全球食品行业在确保食品产品的安全性和真实性方面面临重大挑战。据估计,食品的经济掺假和假冒行为每年给该行业造成300亿至400亿美元的损失。分析检测在检测食品欺诈方面发挥着至关重要的作用。为确保检测结果的计量溯源性和可比性,使用参考物质(RM)至关重要。本文介绍了参考物质在食品真实性检测中的作用,包括它们在方法验证、校准、质量控制以及传统测量尺度定义中的应用。还综述了可用于测量程序以鉴定食品的参考物质的可用性。此外,还探讨了参考物质在靶向掺假物检测方法、用于鉴定食品和食品补充剂的成分参数、同位素测量、非靶向食品真实性检测方法以及转基因生物(GMO)的检测和定量中的应用。本文最后建议开发研究级测试材料或代表性测试材料,以统一非靶向检测方法,并提高不同实验室之间以及不同时间结果的可比性。