朝着非靶向代谢组学研究的质量保证和质量控制迈进。
Towards quality assurance and quality control in untargeted metabolomics studies.
机构信息
National Center for Toxicological Research, US Food and Drug Administration, Jefferson, USA.
School of Biosciences, Phenome Centre Birmingham and Institute for Metabolism and Systems Research, University of Birmingham, Birmingham, B15 2TT, UK.
出版信息
Metabolomics. 2019 Jan 3;15(1):4. doi: 10.1007/s11306-018-1460-7.
We describe here the agreed upon first development steps and priority objectives of a community engagement effort to address current challenges in quality assurance (QA) and quality control (QC) in untargeted metabolomic studies. This has included (1) a QA and QC questionnaire responded to by the metabolomics community in 2015 which recommended education of the metabolomics community, development of appropriate standard reference materials and providing incentives for laboratories to apply QA and QC; (2) a 2-day 'Think Tank on Quality Assurance and Quality Control for Untargeted Metabolomic Studies' held at the National Cancer Institute's Shady Grove Campus and (3) establishment of the Metabolomics Quality Assurance and Quality Control Consortium (mQACC) to drive forward developments in a coordinated manner.
我们在此描述了一项社区参与计划的初步商定发展步骤和优先目标，该计划旨在解决非靶向代谢组学研究中当前在质量保证 (QA) 和质量控制 (QC) 方面面临的挑战。这包括：(1) 2015 年代谢组学社区对 QA 和 QC 调查问卷的回应，该问卷建议对代谢组学社区进行教育，开发适当的标准参考物质，并为实验室应用 QA 和 QC 提供激励；(2) 在国立癌症研究所 Shady Grove 校园举行的为期两天的“非靶向代谢组学研究的质量保证和质量控制思想研讨会”；(3) 建立代谢组学质量保证和质量控制联盟 (mQACC)，以协调一致的方式推动发展。
Zotero 插件