Kong Hanxin, Ying Hao, Yang Jianhong
Department of Neurology, Ningbo First Hospital, Ningbo, Zhejiang, China.
Front Med (Lausanne). 2025 Jan 14;11:1513771. doi: 10.3389/fmed.2024.1513771. eCollection 2024.
is a very rare pathogen that causes intracranial infection. It is commonly found in immunocompromised patients and is resistant to multiple antibiotics. In this case report, we present a case of human central nervous system infection caused by , which was initially misdiagnosed as demyelinating disease due to the specific imaging findings. This case had concurrent uremia and a good response to meropenem under continuous peritoneal dialysis. The diagnosis is mainly based on cerebrospinal fluid analysis and targeted genetic testing by next generation sequencing (NGS). However, the patient had a poor prognosis due to uncontrollable gastrointestinal bleeding and related complications during long-term bed rest. We hope that this case will attract more attention and provide relevant reference for the diagnosis and treatment of other similar patients.
是一种非常罕见的可引起颅内感染的病原体。它常见于免疫功能低下的患者，并且对多种抗生素耐药。在本病例报告中，我们呈现了一例由 引起的人类中枢神经系统感染病例，该病例最初因特定的影像学表现被误诊为脱髓鞘疾病。此病例并发尿毒症，在持续腹膜透析下对美罗培南反应良好。诊断主要基于脑脊液分析和下一代测序（NGS）进行的靶向基因检测。然而，患者因长期卧床期间无法控制的胃肠道出血及相关并发症，预后较差。我们希望该病例能引起更多关注，并为其他类似患者的诊断和治疗提供相关参考。
