Nehme Mayssam, Zaballa Maria Eugenia, Rouzinov Serguei, Lamour Julien, Stringhini Silvia, Guessous Idris
Division of Primary Care Medicine, Geneva University Hospitals, Geneva, Switzerland.
Faculty of Medicine, University of Geneva, Geneva, Switzerland.
Front Cardiovasc Med. 2025 Jan 14;11:1434141. doi: 10.3389/fcvm.2024.1434141. eCollection 2024.
The COVID-19 pandemic, starting in 2020, raised concerns about potential long-term health impacts, including its effects on cardiovascular health and related biomarkers. This study part of the Bus Santé in Geneva, Switzerland, compared cardiovascular and metabolic profiles pre- (2016-2019) and post-pandemic (2023-2024) among individuals aged 30-75.
Participants completed questionnaires and underwent a clinical visit, including a physical examination and fasting blood test to assess lipid and glycemic profiles. Linear regression was used to estimate results including mean systolic and diastolic blood pressure, cholesterol, and glycemic profiles, after adjusting for age, sex, smoking, and socioeconomic status. Quantile regression models were used to estimate median values.
A total of 4,558 participants were included. The study observed modest declines in mean glucose, cholesterol, HDL, and LDL levels post-pandemic, with stable blood pressure. The prevalence and treatment rates of diabetes, hypertension, and dyslipidemia remained consistent. Unawareness of these conditions was stable.
Despite initial fears of a pandemic-induced health debt, results indicate healthy cardiovascular profiles post-pandemic, likely driven by improved lifestyle behaviors. This study highlights the importance of monitoring of cardiovascular health and suggests that lifestyle improvements may offset potential adverse pandemic effects in developed nations like Switzerland.
始于2020年的新冠疫情引发了人们对潜在长期健康影响的担忧，包括其对心血管健康及相关生物标志物的影响。这项瑞士日内瓦公交健康研究的一部分，比较了30至75岁人群在疫情前（2016 - 2019年）和疫情后（2023 - 2024年）的心血管和代谢状况。
参与者完成问卷调查并接受临床检查，包括体格检查和空腹血液检测以评估血脂和血糖状况。在对年龄、性别、吸烟情况和社会经济地位进行调整后，使用线性回归来估计包括平均收缩压和舒张压、胆固醇及血糖状况等结果。分位数回归模型用于估计中位数。
共纳入4558名参与者。研究观察到疫情后平均血糖、胆固醇、高密度脂蛋白和低密度脂蛋白水平有适度下降，血压保持稳定。糖尿病、高血压和血脂异常的患病率及治疗率保持一致。对这些疾病的知晓情况稳定。
尽管最初担心疫情会导致健康负担，但结果表明疫情后心血管状况良好，这可能是由生活方式改善所致。本研究强调了监测心血管健康的重要性，并表明生活方式的改善可能抵消像瑞士这样的发达国家中疫情潜在的不利影响。
