Kumar Raju Suresh, Alqarni Abdulaziz Abdullah, Alghamdi Musaad Jamaan, Alharbi Saad Amer, Alsharef Omar Loutfi, Ahmed Mohamed Eldigire
Department of Basic Sciences, College of Science and Health Professions (COSHP), King Saud bin Abdulaziz University for Health Sciences (KSAU-HS), Jeddah, Saudi Arabia.
King Abdullah International Medical Research Center (KAIMRC), Jeddah, Saudi Arabia.
J Med Life. 2024 Dec;17(12):1067-1071. doi: 10.25122/jml-2024-0378.
The risk of cardiovascular disease differs among various ethnic groups, highlighting disparities in cardiovascular health among different populations. While multiple studies from other countries have looked at changes in physiological parameters during autonomic function tests like isometric handgrip and cold pressor tests, no correlational research has been done in Saudi Arabia. This lacuna underscores the importance of examining the relationship between cardiorespiratory parameters in young Saudi Arabian individuals during these tests. This study aimed to determine the correlation between the isometric handgrip and cold pressor tests and physiological parameters in healthy young Saudi Arabian college students. A single-arm interventional study was conducted with a cohort of 65 healthy young adult Saudi college students, including male and female participants. A point estimate was calculated with a 95% confidence level. Physiological parameters were analyzed and compared at rest and during isometric handgrip and cold pressor tests. The study involved participants with an average age of 21.12 ± 1.02, predominantly male students. A significant impact was observed only in respiratory rate ( = 0.007) during the isometric handgrip and cold pressor tests. In contrast, blood pressure parameters and arterial oxygen saturation values showed no statistical significance during both tests. This sheds light on their autonomic responses to physiological stressors and contributes to our understanding of cardiovascular health across diverse populations, guiding future interventions for global improvements in cardiorespiratory outcomes.
心血管疾病的风险在不同种族群体中存在差异,这凸显了不同人群在心血管健康方面的差距。虽然其他国家的多项研究考察了诸如等长握力和冷加压试验等自主神经功能测试期间生理参数的变化,但沙特阿拉伯尚未开展相关性研究。这一空白凸显了在这些测试中研究沙特阿拉伯年轻个体心肺参数之间关系的重要性。本研究旨在确定等长握力和冷加压试验与健康沙特阿拉伯年轻大学生生理参数之间的相关性。对65名健康沙特年轻成年大学生(包括男性和女性参与者)进行了单臂干预研究。计算了95%置信水平下的点估计值。在静息状态、等长握力试验和冷加压试验期间对生理参数进行了分析和比较。该研究的参与者平均年龄为21.12±1.02岁,主要是男学生。在等长握力和冷加压试验期间,仅观察到呼吸频率有显著影响(P = 0.007)。相比之下,在两项试验中血压参数和动脉血氧饱和度值均无统计学意义。这揭示了他们对生理应激源的自主反应,并有助于我们了解不同人群的心血管健康,为未来改善心肺结局的全球干预措施提供指导。