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Severe Respiratory Acidosis-induced Involuntary Hyper defecation: The Role of Medullary Caudal Raphe Nuclei.

作者信息

Khandelwal Ankur, Dikshit Priyadarshi, Deori Pankaj, Baidya Dalim Kumar

机构信息

Department of Anaesthesiology, Critical Care and Pain Medicine, All India Institute of Medical Sciences (AIIMS), Guwahati,Silbharal, Changsari, Assam, India.

Department of Neurosurgery, All India Institute of Medical Sciences (AIIMS), Guwahati, Silbharal, Changsari, Assam, India.

出版信息

Niger Med J. 2025 Jan 10;65(6):1194-1196. doi: 10.60787/nmj.v65i6.665. eCollection 2024 Nov-Dec.

DOI:10.60787/nmj.v65i6.665
PMID:39877514
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11770658/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7bbe/11770658/9376e46d783b/nmj-65-1194-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7bbe/11770658/f069248f4af4/nmj-65-1194-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7bbe/11770658/9376e46d783b/nmj-65-1194-f2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7bbe/11770658/f069248f4af4/nmj-65-1194-f1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/7bbe/11770658/9376e46d783b/nmj-65-1194-f2.jpg

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本文引用的文献

1
Understanding the physiology of human defaecation and disorders of continence and evacuation.了解人类排便的生理学以及控便和排便障碍。
Nat Rev Gastroenterol Hepatol. 2021 Nov;18(11):751-769. doi: 10.1038/s41575-021-00487-5. Epub 2021 Aug 9.
2
Medullary raphe nuclei activate the lumbosacral defecation center through the descending serotonergic pathway to regulate colorectal motility in rats.延髓中缝核通过下行 5-羟色胺能通路激活腰骶排便中枢，调节大鼠结肠直肠运动。
Am J Physiol Gastrointest Liver Physiol. 2018 Mar 1;314(3):G341-G348. doi: 10.1152/ajpgi.00317.2017. Epub 2017 Nov 22.
3
Medullary serotonin neurons and central CO2 chemoreception.
延髓5-羟色胺能神经元与中枢二氧化碳化学感受
Respir Physiol Neurobiol. 2009 Aug 31;168(1-2):49-58. doi: 10.1016/j.resp.2009.04.014. Epub 2009 Apr 24.
4
Serotonergic neurons as carbon dioxide sensors that maintain pH homeostasis.作为维持pH稳态的二氧化碳传感器的5-羟色胺能神经元。
Nat Rev Neurosci. 2004 Jun;5(6):449-61. doi: 10.1038/nrn1409.
5
Pelvic afferent reflex control of rectal motility and lumbar colonic efferent discharge mediated by the pontine sympatho-inhibitory region in guinea pigs.豚鼠中脑桥交感抑制区介导的盆腔传入神经对直肠运动和腰段结肠传出放电的反射性控制。
Pflugers Arch. 1985 Feb;403(2):164-9. doi: 10.1007/BF00584095.