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一种在手术室对肺结节进行快速现场定位并随后进行肺切除的新技术:病例系列报告

A novel technique for rapid localization of pulmonary nodules on-site in operating room followed by lung resection: a case series.

作者信息

Huang Wei, Zhang Chengcheng, Zeng Weibiao, Lin Dong, Fan Jiang, Wu Liang

机构信息

Department of Thoracic Surgery, Shanghai General Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, People's Republic of China.

出版信息

Int J Surg. 2025 Mar 1;111(3):2331-2337. doi: 10.1097/JS9.0000000000002256.

Abstract

BACKGROUND

The localization of pulmonary nodules is crucial for surgical intervention. However, a safe, simple, and efficient method remains elusive. This study aims to evaluate the safety and feasibility of a newly developed preoperative localization method for pulmonary nodules called Rapid Localization of Pulmonary Nodules On-Site (RLPN-OS).

METHODS

This study is a single-center, single-arm prospective investigation that collects and analyses the clinical data of patients who underwent RLPN-OS and lung resection, primarily evaluating the safety and feasibility of this technique.

RESULTS

A total of 200 lung nodules from 190 patients who underwent RLPN-OS and partial lobectomy were included in this study. The success rate of localization was 98.0%, and minor intercostal bleeding was observed in 3 (1.5%) cases. All targeted lesions were located and resected successfully. No patients reported experiencing anxiety or pain during or after the procedure.

CONCLUSIONS

This novel RLPN-OS technology represents a safe, feasible, patient-friendly, and cost-effective method for lung nodule localization. It has the potential to serve as an alternative to traditional CT-guided percutaneous localization techniques.

摘要

背景

肺结节的定位对于手术干预至关重要。然而,一种安全、简单且有效的方法仍然难以找到。本研究旨在评估一种新开发的用于肺结节的术前定位方法——肺结节现场快速定位(RLPN-OS)的安全性和可行性。

方法

本研究是一项单中心、单臂前瞻性调查,收集并分析接受RLPN-OS和肺切除术患者的临床数据,主要评估该技术的安全性和可行性。

结果

本研究纳入了190例行RLPN-OS和部分肺叶切除术患者的200个肺结节。定位成功率为98.0%,3例(1.5%)出现轻微肋间出血。所有目标病灶均成功定位并切除。无患者报告在手术期间或术后出现焦虑或疼痛。

结论

这种新型的RLPN-OS技术是一种安全、可行、对患者友好且具有成本效益的肺结节定位方法。它有可能成为传统CT引导下经皮定位技术的替代方法。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2082/12372744/9ddad0a7d9f6/js9-111-2331-g001.jpg

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