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多发性硬化症患者不同年龄组的性功能障碍与生活质量:一项前瞻性横断面分析。

Sexual dysfunction and quality of life across age groups in multiple sclerosis patients: a prospective cross-sectional analysis.

作者信息

Dehghaniathar Reza, Faegh Ali, Hajiakhoundi Fahimeh, Shakiba Behnam, Najjar Zeynab

机构信息

Urology Department, Firoozgar Hospital, School of Medicine, Iran University of Medical Sciences, Vali-e-asr St, 1593748711, Tehran, Iran.

School of Medicine, Alborz University of Medical Sciences, Karaj, Iran.

出版信息

BMC Neurol. 2025 Jan 29;25(1):42. doi: 10.1186/s12883-025-04054-2.

Abstract

INTRODUCTION

As the most frequent chronic neurological disorder in young adults, Multiple sclerosis (MS) significantly affects neurological function, particularly the autonomic nervous system. While the physical symptoms are visible, MS also causes hidden effects like sexual dysfunction. Research indicates that sexual disorders are more prevalent in MS patients compared to other neurological conditions and are approximately five times more common than in the general population. This study utilized the Sexual Intimacy and Desires in MS Patients Questionnaire (MSISQ-19) and the Quality of Life in Patients with Multiple Sclerosis Questionnaire to investigate the impact of sexual disorders on the quality of life in MS patients.

METHODS

This cross-sectional study was conducted on MS patients attending the MS clinic in 2022 and 2023. Eighty patients were randomly selected, and data were collected using the MSISQ-19 and MSQOL-54 questionnaires. The results were analyzed to establish the impact of sexual disorders on quality of life.

RESULTS

59 women and 21 men with MS were included. The Physical Health Scale (PHC) had a mean score of 51.6 (SD = 20.2), and the Mental Health Scale (MHC) had a mean score of 57.8 (SD = 20.5). Age appeared to influence physical health scores, with the youngest group (20-30 years) scoring highest and the oldest group (51-65 years) scoring lowest.

DISCUSSION AND CONCLUSION

The present study found that primary, secondary, and tertiary sexual disorders are common in MS patients across all age groups and genders. These findings highlight the need for increased attention, research, and treatment interventions for sexual dysfunction in MS patients.

摘要

引言

作为年轻成年人中最常见的慢性神经疾病,多发性硬化症(MS)会显著影响神经功能,尤其是自主神经系统。虽然身体症状是可见的,但MS也会导致性功能障碍等隐藏影响。研究表明,与其他神经疾病相比,性功能障碍在MS患者中更为普遍,其发生率大约是普通人群的五倍。本研究使用多发性硬化症患者性亲密与欲望问卷(MSISQ - 19)和多发性硬化症患者生活质量问卷来调查性功能障碍对MS患者生活质量的影响。

方法

本横断面研究于2022年和2023年对前往MS诊所就诊的患者进行。随机选取80名患者,使用MSISQ - 19和MSQOL - 54问卷收集数据。对结果进行分析以确定性功能障碍对生活质量的影响。

结果

纳入了59名患有MS的女性和21名男性。身体健康量表(PHC)的平均得分为51.6(标准差 = 20.2),心理健康量表(MHC)的平均得分为57.8(标准差 = 20.5)。年龄似乎会影响身体健康得分,最年轻的组(20 - 30岁)得分最高,最年长的组(51 - 65岁)得分最低。

讨论与结论

本研究发现,原发性、继发性和第三发性性功能障碍在所有年龄组和性别的MS患者中都很常见。这些发现凸显了对MS患者性功能障碍需要更多关注、研究和治疗干预的必要性。

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