Ghajarzadeh Mahsa, Jalilian Rozita, Mohammadifar Mehdi, Sahraian Mohammad Ali, Azimi Amirreza
Department of Neurology, Brain and Spinal Injury Research Center, Tehran University of Medical Sciences, Tehran, Iran
Department of Neurology, Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran
Acta Med Iran. 2014;52(4):315-8.
Multiple sclerosis (MS) is an inflammatory disease of central nervous system (CNS) and sexual dysfunction (SD) is one of the most common disabilities of MS women. The aim of this study was to determine sexual function of women with MS (multiple sclerosis). One hundred definite MS patients MS patients and fifty age-matched healthy controls were enrolled. Demographic data (sex, age), duration of the disease and disease pattern extracted from patient's files and Kurtzke Expanded Disability Status Scale (EDSS) recorded for each patient by an expert neurologist. Participants were asked to answer the valid and reliable Persian version of Beck depression inventory (BDI) and Female Sexual Function Index (FSFI) questionnaires. The total FSFI score and subscale scores differed significantly between the MS patients and the controls. There was a significant negative correlation between EDSS and FSFI scores (rho=-0.44, P<0.001) and significant positive correlation between EDSS and BDI (rho=0.36, P<0.001) in patients. Mean BDI and all subscales of FSFI differed significantly between patients with total FSFI score higher and lower than 26.55. Sexual dysfunction should be considered in women with multiple sclerosis.
多发性硬化症（MS）是一种中枢神经系统（CNS）的炎症性疾病，性功能障碍（SD）是患有MS的女性最常见的残疾之一。本研究的目的是确定患有MS（多发性硬化症）的女性的性功能。招募了100名确诊的MS患者和50名年龄匹配的健康对照者。从患者病历中提取人口统计学数据（性别、年龄）、疾病持续时间和疾病模式，并由一名神经科专家为每位患者记录Kurtzke扩展残疾状态量表（EDSS）。要求参与者回答波斯语版本的有效且可靠的贝克抑郁量表（BDI）和女性性功能指数（FSFI）问卷。MS患者和对照组之间的FSFI总分及各子量表得分存在显著差异。患者的EDSS与FSFI得分之间存在显著负相关（rho=-0.44，P<0.001），EDSS与BDI之间存在显著正相关（rho=0.36，P<0.001）。FSFI总分高于和低于26.55的患者之间，平均BDI及FSFI的所有子量表存在显著差异。患有多发性硬化症的女性应考虑性功能障碍。
