Clinic of Neurology, Clinical Center of Serbia, Dr Subotica 6, 11000, Belgrade, Serbia.
Faculty of Medicine, University of Belgrade, Dr Subotica 8, 11000, Belgrade, Serbia.
Acta Neurol Belg. 2020 Aug;120(4):791-797. doi: 10.1007/s13760-020-01323-4. Epub 2020 Mar 11.
Multiple sclerosis (MS) is the most common chronic neurological disorder in young adults, with numerous potential effects on neurologic function. Sexual dysfunction (SD) is a common and very stressful one in persons with MS and represents a significant burden of disease. It has been shown that proportion of SD in MS is greater than in other neurological diseases, and almost five times higher than in the general population. Since there is no consistent definition in the literature for the diagnosis of SD, various studies reported a prevalence of SD of 40-80% in women and 50-90% in men with MS. The nature of sexual changes in this chronic illness is best defined as primary, secondary, and tertiary. Recently, it has been emphasized that detailed sexual history is crucial for all SD assessments and diagnoses. Committee 3 of the international consultation on sexual medicine suggested an updating algorithm for diagnostic evaluation of SD in both genders, with specific recommendations related to sexual history taking and diagnostic evaluation. Because treatments and preventive strategies might manage SD, it is necessary to increase the focus on these aspects of the disease when counselling patients. Management of SD should be comprehensive because the symptoms could be somatic, psychological, or related to relationship problems.
多发性硬化症（MS）是年轻人中最常见的慢性神经系统疾病，对神经系统功能有多种潜在影响。性功能障碍（SD）是多发性硬化症患者中常见且非常严重的问题，是疾病的一个重要负担。有研究表明，多发性硬化症患者中 SD 的比例高于其他神经系统疾病，几乎是普通人群的五倍。由于文献中对 SD 的诊断没有一致的定义，因此各种研究报告的多发性硬化症患者中女性 SD 的患病率为 40-80%，男性为 50-90%。这种慢性疾病中性功能变化的性质最好定义为原发性、继发性和继发性。最近，人们强调详细的性史对于所有 SD 评估和诊断都至关重要。国际性功能医学咨询委员会建议更新两性 SD 诊断评估的算法，其中包括与性史采集和诊断评估相关的具体建议。因为治疗和预防策略可能会管理 SD，因此在为患者提供咨询时，有必要更加关注疾病的这些方面。SD 的管理应该是全面的，因为症状可能是躯体的、心理的或与人际关系问题有关。
