Jerban Saeed, Tabbaa Suzanne M, Caldwell Paul E, Jones Kristofer J, Bugbee William, Crawford Dennis C, Chang Eric Y
Department of Radiology, University of California, San Diego, La Jolla, CA, USA.
Department of Orthopaedic Surgery, University of California San Francisco, San Francisco, CA, USA.
Cartilage. 2025 Jan 29:19476035251314109. doi: 10.1177/19476035251314109.
Accurate donor-recipient matching of the femoral condyle radius of curvature (ROC) in osteochondral allograft (OCA) transplantation may aid in minimizing articular surface incongruities. Matching linear femorotibial dimensions, such as the femoral condyle anterior-posterior length (APL), femoral condyle width (lateral-medial length, LML), femoral hemicondyle width (HCW), and tibial plateau width (TPW), can provide similar results if they correlate well with ROC. This study investigates the relationship between femorotibial dimensions and ROC at the cartilage surface using magnetic resonance imaging (MRI).
Deidentified MRI images of 63 patients (35 men, 33 ± 10 years old, and 28 women, 27 ± 8 years old) were analyzed. Axial images were used for APL, LML, and TPW (TPW-Ax) measurements, while coronal images were used for HCW and TPW (TPW-Cor) measurements. Cartilage was segmented in true sagittal images at the medial femoral condyle (MFC) and lateral femoral condyle (LFC) to calculate their specific cartilage surface ROCs. Linear regression models were used to determine the relationship between the femorotibial dimensions and ROC.
Cartilage ROC was significantly correlated with all the linear femorotibial dimensions at the MFC ( < 0.01, = 0.78, 0.69, 0.67, 0.59, and 0.37 for ROC correlations with APL, LML, TPW-Ax, TPW-Cor, and HCW, respectively), and the LFC ( < 0.01, = 0.81, 0.61, 0.56, 0.54, and 0.41 for ROC correlations with APL, LML, TPW-Ax, TPW-Cor, and HCW, respectively).
The APL was the most predictive femorotibial dimension of the cartilage surface ROC. Donor-recipient APL matching in OCA transplantation may provide a similar level of matching to that achievable by direct ROC measurements. The APL matching may help reduce cartilage incongruities, particularly for patients with large osteochondral lesions, in which the ROC measurement cannot be accurately determined.
在骨软骨异体移植（OCA）中，精确匹配股骨髁曲率半径（ROC）的供体与受体，可能有助于将关节面不匹配程度降至最低。如果线性股骨胫尺寸，如股骨髁前后长度（APL）、股骨髁宽度（内外侧长度，LML）、股骨半髁宽度（HCW）和胫骨平台宽度（TPW）与ROC有良好的相关性，那么匹配这些尺寸可能会得到类似的结果。本研究使用磁共振成像（MRI）来探究软骨表面股骨胫尺寸与ROC之间的关系。
分析了63例患者（35名男性，33±10岁；28名女性，27±8岁）的匿名MRI图像。轴向图像用于测量APL、LML和TPW（TPW-Ax），而冠状图像用于测量HCW和TPW（TPW-Cor）。在股骨内侧髁（MFC）和外侧髁（LFC）的真实矢状图像中对软骨进行分割，以计算其特定软骨表面的ROC。使用线性回归模型来确定股骨胫尺寸与ROC之间的关系。
在MFC处，软骨ROC与所有线性股骨胫尺寸均显著相关（ROC与APL、LML、TPW-Ax、TPW-Cor和HCW的相关性分别为<0.01，r = 0.78、0.69、0.67、0.59和0.37）；在LFC处也显著相关（ROC与APL、LML、TPW-Ax、TPW-Cor和HCW的相关性分别为<0.01，r = 0.81、0.61、0.56、0.54和0.41）。
APL是软骨表面ROC最具预测性的股骨胫尺寸。在OCA移植中进行供体与受体的APL匹配，可能会提供与直接测量ROC相当的匹配水平。APL匹配可能有助于减少软骨不匹配，特别是对于那些无法准确确定ROC测量值的大骨软骨损伤患者。
