Bojja Srikaran, Javed Nismat, Molina Marcos, Smith Harriet, Khaja Misbahuddin
Internal Medicine, BronxCare Health System, New York City, USA.
Internal Medicine, BronxCare Health System/Icahn School of Medicine at Mount Sinai, New York City, USA.
Cureus. 2024 Dec 30;16(12):e76640. doi: 10.7759/cureus.76640. eCollection 2024 Dec.
Ovarian sex cord-stromal tumors (SCST) are a rare subset of ovarian neoplasms originating from supportive tissues surrounding oocytes. Despite their rarity, prompt diagnosis and management are crucial due to their potential for diverse clinical presentations and the need to optimize patient outcomes. A 25-year-old female patient was initially diagnosed with pyelonephritis but later discovered to have a large right adnexal mass suspected to be a tubo-ovarian abscess. Further evaluation, including tumor markers and imaging, suggested the possibility of a germ cell tumor or sex-cord stromal tumor, leading to surgical intervention. During surgery, a necrotic tubo-ovarian mass with torsion was found and removed, with subsequent pathology confirming a benign stromal tumor. The patient experienced a smooth recovery postoperatively. The management of ovarian SCST, which is rare and has varied clinical presentations, requires accurate diagnosis and a customized treatment approach. These typically benign tumors can produce steroid hormones, leading to distinct symptoms like virilization or estrogen excess. Diagnostic tools include imaging and tumor markers, while surgical options range from conservative to extensive based on specific tumor and patient characteristics. Post-treatment surveillance involves monitoring symptoms and tumor markers. Advancing the understanding and care of these tumors relies on ongoing research and collaborative, multidisciplinary efforts to improve patient outcomes.
卵巢性索间质肿瘤(SCST)是卵巢肿瘤中罕见的一类,起源于围绕卵母细胞的支持组织。尽管其罕见,但由于其临床表现多样且需要优化患者预后,及时诊断和管理至关重要。一名25岁女性患者最初被诊断为肾盂肾炎,但后来发现右侧附件有一个大肿块,怀疑是输卵管卵巢脓肿。进一步评估,包括肿瘤标志物和影像学检查,提示可能是生殖细胞肿瘤或性索间质肿瘤,遂进行手术干预。手术中发现一个坏死的扭转性输卵管卵巢肿块并将其切除,随后病理证实为良性间质肿瘤。患者术后恢复顺利。卵巢SCST罕见且临床表现各异,其管理需要准确诊断和定制化治疗方法。这些通常为良性的肿瘤可产生甾体激素,导致如男性化或雌激素过多等明显症状。诊断工具包括影像学检查和肿瘤标志物,而手术选择根据特定肿瘤和患者特征从保守到广泛不等。治疗后监测包括监测症状和肿瘤标志物。增进对这些肿瘤的理解和护理依赖于持续的研究以及多学科协作努力以改善患者预后。