Kadam Abhinav, Kinkar Jiwan, Toshniwal Saket S, Kumar Sunil, Naseri Suhit
Department of Medicine, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Department of Neurology, Jawaharlal Nehru Medical College, Datta Meghe Institute of Higher Education and Research, Wardha, IND.
Cureus. 2024 Dec 30;16(12):e76617. doi: 10.7759/cureus.76617. eCollection 2024 Dec.
Brain edema and neurological symptoms are the hallmarks of the uncommon disease known as posterior reversible encephalopathy syndrome (PRES), which can have several etiological causes. Since the etiology determines the course of treatment, diagnosis is crucial. There have only been 14 cases of PRES associated with inflammatory bowel disorders documented. We present an exciting and novel presentation of a 19-year-old female who was admitted to the hospital with a diagnosis of acute severe colitis and experienced multiple seizure episodes. She was later diagnosed with atypical PRES on an MRI brain, which showed posterior white matter T2 lesions with anterior extension. She was started on anti-epileptic drugs and showed regression of symptoms within 24 hours. The follow-up MRI showed complete resolution. Furthermore, a colonoscopy was done, which was suggestive of ulcerative colitis. The association of ulcerative colitis with atypical PRES is rarely documented in the literature.
脑水肿和神经症状是一种名为后部可逆性脑病综合征（PRES）的罕见疾病的特征，该疾病可能有多种病因。由于病因决定治疗方案，因此诊断至关重要。仅有14例与炎症性肠病相关的PRES病例被记录在案。我们报告了一例令人关注的新病例，一名19岁女性因急性重症结肠炎入院，经历了多次癫痫发作。后来她的脑部MRI显示后部白质T2病变并向前延伸，被诊断为非典型PRES。她开始接受抗癫痫药物治疗，症状在24小时内有所缓解。后续MRI显示病变完全消退。此外，结肠镜检查提示为溃疡性结肠炎。溃疡性结肠炎与非典型PRES的关联在文献中鲜有记载。
