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姜黄素与蓝光介导的光动力疗法治疗复发性唇疱疹：一例报告

Photodynamic Therapy Mediated by Curcumin and Blue Light for Recurrent Herpes Labialis: A Case Report.

作者信息

Khalil Marwa, Hamadah Omar

机构信息

Department of Oral Medicine, Faculty of Dentistry Damascus University Damascus Syria.

出版信息

Clin Case Rep. 2025 Jan 29;13(2):e70160. doi: 10.1002/ccr3.70160. eCollection 2025 Feb.

DOI:10.1002/ccr3.70160
PMID:39882155
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11775917/
Abstract

This study is the first to use photodynamic therapy (PDT) mediated by curcumin and blue light for the treatment of recurrent herpes labialis. According to our study, PDT effectively accelerated lesion healing and reduced its recurrence. PDT may represent a promising, safe, and cost-effective treatment option for this challenging disease.

摘要

本研究首次使用姜黄素和蓝光介导的光动力疗法（PDT）治疗复发性唇疱疹。根据我们的研究，光动力疗法有效加速了病灶愈合并减少了复发。对于这种具有挑战性的疾病，光动力疗法可能是一种有前景、安全且具有成本效益的治疗选择。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50ca/11775917/d22957c0c7da/CCR3-13-e70160-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50ca/11775917/d22957c0c7da/CCR3-13-e70160-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/50ca/11775917/d22957c0c7da/CCR3-13-e70160-g001.jpg

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本文引用的文献

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Acyclovir-resistant HSV-1 isolates among immunocompromised patients in southern Taiwan: Low prevalence and novel mutations.在台湾南部免疫功能低下的患者中发现耐阿昔洛韦的单纯疱疹病毒-1 分离株：低流行率和新突变。
J Med Virol. 2023 Aug;95(8):e28985. doi: 10.1002/jmv.28985.
2
Antimicrobial blue light: A 'Magic Bullet' for the 21st century and beyond?抗菌蓝光：21 世纪及以后的“灵丹妙药”？
Adv Drug Deliv Rev. 2022 Jan;180:114057. doi: 10.1016/j.addr.2021.114057. Epub 2021 Nov 18.
3
Effectiveness of photodynamic therapy as an adjunct to topical antiviral therapy in the treatment of herpes labialis: A randomized controlled clinical trial.
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Photodiagnosis Photodyn Ther. 2021 Jun;34:102302. doi: 10.1016/j.pdpdt.2021.102302. Epub 2021 Apr 21.
4
Nutraceutical Curcumin with Promising Protection against Herpesvirus Infections and Their Associated Inflammation: Mechanisms and Pathways.具有有望预防疱疹病毒感染及其相关炎症作用的营养保健品姜黄素：作用机制与途径
Microorganisms. 2021 Jan 31;9(2):292. doi: 10.3390/microorganisms9020292.
5
Photodynamic therapy and Acyclovir in the treatment of recurrent herpes labialis: A controlled randomized clinical trial.光动力疗法与阿昔洛韦治疗复发性唇疱疹：一项对照随机临床试验。
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Curcumin and Photobiomodulation in Chronic Viral Hepatitis and Hepatocellular Carcinoma.姜黄素和光生物调节在慢性病毒性肝炎和肝细胞癌中的作用。
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