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Roux-en-Y胃旁路术的环形增强:5年随访结果的倾向评分匹配分析

Ring Augmentation of the Roux-en-Y Gastric Bypass: A Propensity Score Matched Analysis of 5-Year Follow-Up Results.

作者信息

Jense Marijn T F, Bruinsma Floris F E, Nienhuijs Simon W, Liem Ronald S L, de Mheen Perla J Marang-van, Greve Jan Willem M, Boerma Evert-Jan G

机构信息

Zuyderland Medisch Centrum, Sittard, Netherlands.

Maastricht University, Maastricht, Netherlands.

出版信息

Obes Surg. 2025 Mar;35(3):884-893. doi: 10.1007/s11695-025-07706-x. Epub 2025 Jan 30.

Abstract

BACKGROUND

The ring-augmented Roux-en-Y gastric bypass (raRYGB) has been reported to result in higher long-term weight loss compared to regular Roux-en-Y gastric bypass (RYGB). However, the type of ring used varied within studies, leading to heterogeneity in reported results. Therefore, this study compares the 5-year results of RYGB with and without ring augmentation using a specific prefabricated gastric ring.

METHODS

All consecutive patients from a single center who received primary raRYGB between June 1, 2016, and May 31, 2018, with complete 5-year follow-up data were included and compared to a propensity score matched cohort receiving RYGB in the same period from the Dutch Audit for Treatment of Obesity. To ensure fair effect estimation of placing a ring, only RYGB procedures with alimentary and biliopancreatic limb lengths similar to those of the raRYGB were considered eligible. The primary outcome was percentage total weight loss (%TWL). Secondary outcomes included recurrent weight gain (RWG), obesity complication improvement, and complications.

RESULTS

In total, 592 matched patients were analyzed. raRYGB was associated with higher %TWL at 5 years (31.5% versus 28.0%, β = 3.59, 95% CI [2.09-5.09], p < 0.01) and lower odds on RWG (odds ratio = 0.56, 95% CI [0.38-0.83], p < 0.01). Improvement of obesity complications and short-term complication rates were comparable in both groups. After 5 years, 13 patients (4%) had experienced ring-related complications needing reoperation.

CONCLUSIONS

At 5 years, raRYGB was associated with higher %TWL and lower odds on RWG. The occurrence of ring-related complications was limited.

摘要

背景

据报道,与常规 Roux-en-Y 胃旁路术(RYGB)相比,环形增强 Roux-en-Y 胃旁路术(raRYGB)能带来更高的长期体重减轻。然而,各研究中使用的环形装置类型有所不同,导致报告结果存在异质性。因此,本研究使用一种特定的预制胃环,比较了有和没有环形增强的 RYGB 的 5 年结果。

方法

纳入了 2016 年 6 月 1 日至 2018 年 5 月 31 日期间在单一中心接受初次 raRYGB 且有完整 5 年随访数据的所有连续患者,并与荷兰肥胖治疗审计中同期接受 RYGB 的倾向评分匹配队列进行比较。为确保对放置环形装置的效果进行公平评估,仅考虑消化道和胆胰肢长度与 raRYGB 相似的 RYGB 手术为合格。主要结局是总体重减轻百分比(%TWL)。次要结局包括体重反复增加(RWG)、肥胖并发症改善情况和并发症。

结果

总共分析了 592 例匹配患者。raRYGB 在 5 年时与更高的 %TWL 相关(31.5% 对 28.0%,β = 3.59,95% CI [2.09 - 5.09],p < 0.01),且 RWG 的几率更低(优势比 = 0.56,95% CI [0.38 - 0.83],p < 0.01)。两组肥胖并发症的改善情况和短期并发症发生率相当。5 年后,13 例患者(4%)出现了需要再次手术的与环形装置相关的并发症。

结论

在 5 年时,raRYGB 与更高的 %TWL 和更低的 RWG 几率相关。与环形装置相关的并发症发生率有限。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2faa/11906517/ec98ce6bead7/11695_2025_7706_Fig1_HTML.jpg

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