Jense Marijn T F, Bluijssen Kick, De Witte Evelien, Broos Pieter P H L, Schaafsma Boudewijn E, Greve Jan Willem M, Boerma Evert-Jan G
Zuyderland Medisch Centrum, Sittard, Netherlands.
Maastricht University, Maastricht, Netherlands.
Obes Surg. 2025 Jun 26. doi: 10.1007/s11695-025-07988-1.
The Roux-en-Y gastric bypass (RYGB) is regarded as one of the most effective treatments for obesity. The ring-augmented RYGB (raRYGB), has demonstrated superior long-term weight loss outcomes and better weight maintenance compared to the standard RYGB. There is no agreement regarding the optimal procedure for patients with a BMI >50 kg/m. This study aims to evaluate the effectiveness and safety of ring augmentation of a RYGB with a MiniMizer ring in patients with a BMI >50 kg/m at 2-year follow-up.
This study is a retrospective cohort study performed at the Zuyderland Medical Center in Heerlen and the Nederlandse Obesitas Kliniek Zuid. All patients with a BMI >50 kg/m who underwent a raRYGB with a MiniMizer ring in the period 2016-2021 are included. Total weight loss (TWL), obesity-related complications, and surgical-related complications were analyzed over 2 years post-operative.
A total of 171 patients were included, of whom 78.4% were female, with a median BMI of 54.0 kg/m (51.4-57.7 IQR) and age of 42 (32-52 IQR) years at baseline. The mean % TWL was 15.6 at 3 months, 24.8 at 6 months, 32.1 at 1 year, and 35.2 at 2 years post-operatively. Complications of Clavien Dindo 3 or higher within the first 30 post-operative days were seen in 8 patients (4.7%) of which 1 (0.6%) was ring related.
The raRYGB with a MiniMizer ring in this study population results in high total weight loss results after 2 years. Ring-related complications rates are low. Therefore, we conclude that a raRYGB is an effective and safe treatment option for patients with a BMI >50 kg/m.
Roux-en-Y胃旁路术（RYGB）被认为是治疗肥胖最有效的方法之一。与标准RYGB相比，环形增强RYGB（raRYGB）已显示出更优的长期体重减轻效果和更好的体重维持效果。对于BMI>50 kg/m²的患者，尚无关于最佳手术方式的共识。本研究旨在评估在2年随访期内，使用MiniMizer环对BMI>50 kg/m²的患者进行RYGB环形增强术的有效性和安全性。
本研究是一项在海尔伦的祖德兰德医疗中心和荷兰南部肥胖诊所进行的回顾性队列研究。纳入2016年至2021年期间接受带MiniMizer环的raRYGB手术的所有BMI>50 kg/m²的患者。分析术后2年内的总体重减轻（TWL）、肥胖相关并发症和手术相关并发症。
共纳入171例患者，其中78.4%为女性，基线时BMI中位数为54.0 kg/m²（四分位间距IQR为51.4 - 57.7），年龄为42岁（IQR为32 - 52）。术后3个月时平均TWL百分比为15.6%，6个月时为24.8%，1年时为32.1%，2年时为35.2%。术后30天内出现Clavien Dindo 3级或更高等级并发症的患者有8例（4.7%），其中1例（0.6%）与环相关。
本研究人群中使用MiniMizer环的raRYGB在2年后可实现较高的总体重减轻效果。与环相关的并发症发生率较低。因此，我们得出结论，raRYGB对于BMI>50 kg/m²的患者是一种有效且安全的治疗选择。
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