Chudzińska-Skorupinska Jagoda, Wawrzyńczak Agata, Feliczak-Guzik Agnieszka
Adam Mickiewicz University in Poznań, Faculty of Chemistry, Uniwersytetu Poznańskiego 8, 61-614 Poznań, Poland.
Adam Mickiewicz University in Poznań, Faculty of Chemistry, Uniwersytetu Poznańskiego 8, 61-614 Poznań, Poland.
Adv Colloid Interface Sci. 2025 Apr;338:103415. doi: 10.1016/j.cis.2025.103415. Epub 2025 Jan 27.
Effective delivery of active substances and drugs is an important part of treatment. In order for a drug to work at the right place in the body, it must be transported there in the right way. For this reason, new carriers are being sought for active substances and drugs that can effectively deliver drugs to the target site without causing additional side effects. These include nanoparticles, microneedles, cubosomes and nanogels, among others. Recently, carriers based on biodegradable polymers such as hyaluronic acid or chitosan are becoming popular. In addition, modern carriers are designed to release the active ingredient in response to a specific agent. This paper reviews the literature from the past 5 years on novel delivery systems with medical, agricultural, food and cosmetic applications, with a special emphasis on the use of carbohydrate-based nanocarriers.
活性物质和药物的有效递送是治疗的重要组成部分。为了使药物在体内的正确部位发挥作用，必须以正确的方式将其输送到那里。因此，人们正在寻找新的活性物质和药物载体，这些载体能够有效地将药物输送到靶部位而不引起额外的副作用。其中包括纳米颗粒、微针、立方液晶和纳米凝胶等。最近，基于透明质酸或壳聚糖等可生物降解聚合物的载体正变得越来越流行。此外，现代载体被设计为响应特定因子释放活性成分。本文综述了过去5年关于具有医学、农业、食品和化妆品应用的新型递送系统的文献，特别强调了基于碳水化合物的纳米载体的应用。
