评估PREDAC方法在过去十年（2013 - 2023年）流感疫苗推荐中的表现。
Evaluating the performance of the PREDAC method in flu vaccine recommendations over the past decade (2013-2023).
作者信息
Peng Yousong, Yang Lei, Huang Weijuan, Liu Mi, Ding Xiao, Du Xiangjun, Shu Yuelong, Jiang Taijiao, Wang Dayan
机构信息
Bioinformatics Center, College of Biology, Hunan Provincial Key Laboratory of Medical Virology, Hunan University, Changsha, 410082, China.
National Institute for Viral Disease Control and Prevention, China CDC, Beijing, 102206, China.
出版信息
Virol Sin. 2025 Apr;40(2):288-291. doi: 10.1016/j.virs.2025.01.004. Epub 2025 Jan 28.
• PREDAC is a semi-automated and user-friendly method for flu vaccine recommendations based on HA protein sequences. • PREDAC performed comparably to the WHO in recommending vaccines of influenza A(H3N2) viruses during the period of 2013–2023. • PREDAC can serve as a useful supplement to the traditional approach for flu vaccine recommendations. • More intensive surveillance of antigenic variations in the influenza virus are needed to improve vaccine recommendations.
• PREDAC是一种基于血凝素（HA）蛋白序列的流感疫苗推荐的半自动且用户友好的方法。
• 在2013 - 2023年期间，PREDAC在推荐甲型（H3N2）流感病毒疫苗方面与世界卫生组织（WHO）表现相当。
• PREDAC可作为流感疫苗推荐传统方法的有益补充。
• 需要对流感病毒的抗原变异进行更密集的监测，以改进疫苗推荐。
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