Warner Matthew, Lowe Jonathon, Barnard Ed Benjamin Graham
Emergency Department, British Antarctic Survey Medical Unit, Plymouth, UK.
Emergency Department, British Antarctic Survey Medical Unit, Plymouth, UK
Emerg Med J. 2025 Mar 25;42(4):271-272. doi: 10.1136/emermed-2024-214661.
The early administration of tranexamic acid is recognised as significantly reducing mortality in traumatically injured patients with major haemorrhage, typically given via intravenous or intramuscular routes. In the context of mass casualty events, there may exist multiple traumatically injured casualties that would benefit from tranexamic acid, however, it's administration may be delayed through the need to establish intravenous access. Additionally, if the initial assessment of the traumatically injured casualty is undertaken by an individual who cannot administer intravenous or intramuscular medications, time to administration will be further delayed. This concepts paper seeks to discuss the potential for utilising oral tranexamic acid, in the context of mass casualty events, as an alternative administration route.
早期使用氨甲环酸被认为可显著降低严重出血的创伤患者的死亡率，通常通过静脉或肌肉注射途径给药。在大规模伤亡事件中，可能有多名创伤患者会从氨甲环酸中获益，然而，由于需要建立静脉通路，其给药可能会延迟。此外，如果对创伤患者的初始评估由无法进行静脉或肌肉注射给药的人员进行，给药时间将进一步延迟。本概念文件旨在探讨在大规模伤亡事件中使用口服氨甲环酸作为替代给药途径的可能性。
