Jaldo Mesfin Menza, Joffe Mhireteab WoldeYohannes, Zemedkun Eyasu Samuel
School of Public Health, College of Medicine and Health Sciences, Wachemo University, Hossana, Ethiopia.
Hossana Blood Bank, Hossana, Ethiopia.
BMC Infect Dis. 2025 Jan 30;25(1):143. doi: 10.1186/s12879-025-10550-0.
Human hepatitis is an inflammation of the liver brought on by the DNA virus known as the hepatitis B virus (HBV). Around the world, 240 million people are thought to have HBV in a chronic state. The prevalence of viral hepatitis is extremely high in Africa. Prior reports from various regions of the nation have indicated a variable prevalence of HBV infection.
To estimate the prevalence of HBV infections and associated factors among blood donors in the Hossana blood bank catchment area in August 2023.
A community-based cross-sectional study design was conducted among 546 blood donors in the Hossana blood bank catchment area from August 22 to September 22, 2023. Study participants were included using the system established by the blood bank. Both Binary and multivariable logistic regression analysis was conducted. The association of variables was declared at p-value < 0.05 and strength of association was presented using AOR with a corresponding 95% CI. The adequacy of the model was checked by Hosmer-Lemeshow test.
a total of 546 participant's data was analyzed. The prevalence of HBV among blood donors in the Hossana blood bank catchment area was 7.88 with 95% CI [5.76-10.46]. No participants received post-donation counseling. Having multiple sexual partners (AOR = 5.18, 95% CI: 1.32-20.36), Sharing of sharp material (AOR = 3.66, 95% CI: 1.32-10.13) and tooth extraction (AOR = 5.55, 95% CI: 2.08-14.78) were identified as factors associated with HBV positivity.
In this study, the prevalence of hepatitis B virus was 7.88, which is intermediate. Multiple sexual partners, sharing of sharp material, and tooth extraction were related to the hepatitis b virus. Though post-donation counseling is important for the control and prevention of hepatitis b virus infection, it has been neglected since the establishment of the blood bank we strongly recommend counseling regular donors.
Not applicable.
人类肝炎是由称为乙型肝炎病毒（HBV）的DNA病毒引起的肝脏炎症。据估计，全球有2.4亿人处于慢性HBV感染状态。非洲病毒性肝炎的患病率极高。该国不同地区先前的报告显示HBV感染的患病率各不相同。
估计2023年8月霍萨纳血库服务区域内献血者中HBV感染的患病率及相关因素。
2023年8月22日至9月22日，在霍萨纳血库服务区域内的546名献血者中进行了一项基于社区的横断面研究设计。使用血库建立的系统纳入研究参与者。进行了二元和多变量逻辑回归分析。变量之间的关联在p值<0.05时被判定，关联强度使用调整后的比值比（AOR）及相应的95%置信区间表示。通过Hosmer-Lemeshow检验检查模型的拟合优度。
共分析了546名参与者的数据。霍萨纳血库服务区域内献血者中HBV的患病率为7.88%，95%置信区间为[5.76 - 10.46]。没有参与者接受献血后咨询。有多个性伴侣（AOR = 5.18，95%置信区间：1.32 - 20.36）、共用锐器（AOR = 3.66，95%置信区间：1.32 - 10.13）和拔牙（AOR = 5.55，95%置信区间：2.08 - 14.78）被确定为与HBV阳性相关的因素。
在本研究中，乙型肝炎病毒的患病率为7.88%，处于中等水平。多个性伴侣、共用锐器和拔牙与乙型肝炎病毒有关。尽管献血后咨询对于控制和预防乙型肝炎病毒感染很重要，但自血库建立以来一直被忽视，我们强烈建议对定期献血者进行咨询。
不适用。
