Sankar Sathish, Balakrishnan Pachamuthu, Yong Yean K, Raju Sivadoss, Velu Vijayakumar, Shankar Esaki M, Larsson Marie
Department of Microbiology, Centre for Infectious Diseases, Saveetha Dental College and Hospitals, Saveetha Institute of Medical and Technical Sciences, Chennai 600077, Tamil Nadu, India.
Department of Research, Meenakshi Academy of Higher Education and Research (MAHER), Chennai 600078, Tamil Nadu, India.
Can J Infect Dis Med Microbiol. 2025 Jan 22;2025:6683501. doi: 10.1155/cjid/6683501. eCollection 2025.
The monkeypox (Mpox) virus has emerged as a global public health emergency of international concern recently. The virus that was endemic in West and Central Africa has now been reported with chains of global transmission to several countries. A scoping review was carried out from the relevant literature available from PubMed, Scopus and Web of Science. This comprehensive analysis describes the virus epidemiology, pathogenesis, clinical manifestations, complications including secondary bacterial infections, diagnosis, treatment and vaccination. The article underscores the significance of key viral and immune mediators of infection and discusses updated recommendations on therapeutic strategies and vaccination.
猴痘病毒最近已成为引起国际关注的全球突发公共卫生事件。这种在西非和中非流行的病毒现已报告在全球多地传播至多个国家。我们从PubMed、Scopus和Web of Science等相关文献中进行了一项范围综述。这项全面分析描述了该病毒的流行病学、发病机制、临床表现、并发症（包括继发性细菌感染）、诊断、治疗和疫苗接种情况。本文强调了感染的关键病毒和免疫介质的重要性，并讨论了关于治疗策略和疫苗接种的最新建议。
