Urmi Taslima Jamal, Islam Md Rabiul
Department of Pharmacy University of Asia Pacific Farmgate Dhaka Bangladesh.
School of Pharmacy, BRAC University Merul Badda Dhaka Bangladesh.
Health Sci Rep. 2024 Dec 30;8(1):e70306. doi: 10.1002/hsr2.70306. eCollection 2025 Jan.
In 2022, the monkeypox (mpox) outbreak was declared a public health emergency of international concern. The emergence of a new strain in the Democratic Republic of the Congo and its identification with neighboring countries led to the declaration of a public health emergency in 2024. The objective is to focus on the recent outbreak that led to its declaration as a Public Health Emergency of International Concern, assess the significant global public health threat posed by the newly identified class, and explore effective strategies to address this situation.
The present review searched information from databases (PubMed and Scopus), WHO, and the European Centre for Disease Prevention and Control. The search methods followed database-specific criteria. Key terms included mpox, prevalence, public health emergency, treatment, new variant, prevention, and strategy. We reviewed and extracted information from the relevant literature.
Mpox has been endemic in the Democratic Republic of the Congo for over a decade, with a consistent annual rise in reported cases. In August 2024, at least 13 African countries have confirmed 2,863 cases and 517 fatalities. The recent emergence and transmission of a new strain, which appears to be predominantly spreading through sexual networks, along with its identification in neighboring countries, raises significant concerns for public health.
The emergence of the new clade of mpox represents a critical public health challenge that necessitates immediate and coordinated global response efforts. By addressing the current outbreak comprehensively, we can mitigate its impact and safeguard public health across affected regions.
2022年，猴痘疫情被宣布为国际关注的突发公共卫生事件。刚果民主共和国出现新毒株并在邻国被发现，导致2024年宣布突发公共卫生事件。目的是聚焦导致其被宣布为国际关注的突发公共卫生事件的近期疫情，评估新发现毒株对全球公共卫生构成的重大威胁，并探索应对这一情况的有效策略。
本综述检索了数据库（PubMed和Scopus）、世界卫生组织及欧洲疾病预防与控制中心的信息。检索方法遵循各数据库的特定标准。关键词包括猴痘、患病率、突发公共卫生事件、治疗、新变种、预防和策略。我们对相关文献进行了综述并提取了信息。
猴痘在刚果民主共和国呈地方流行已逾十年，报告病例数逐年持续上升。2024年8月，至少13个非洲国家已确诊2863例，517人死亡。新毒株的近期出现和传播，似乎主要通过性网络传播，且在邻国被发现，引起了对公共卫生的重大担忧。
猴痘新分支的出现是一项严峻的公共卫生挑战，需要立即开展全球协调应对行动。通过全面应对当前疫情，我们可以减轻其影响并保护受影响地区的公众健康。
